Relation between serum cystatin C level and brachial–ankle pulse wave velocity in Chinese general population
Background: The purpose of the study is to evaluate whether serum cystatin C level is associated with arterial stiffness independent of other risk factors in Chinese general population. Hypothesis: Cystatin C is a predictable marker of arterial stiffness in Chinese general population. Methods: Subje...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2018-04-01
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| Series: | Clinical and Experimental Hypertension |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/10641963.2016.1248769 |
| Summary: | Background: The purpose of the study is to evaluate whether serum cystatin C level is associated with arterial stiffness independent of other risk factors in Chinese general population. Hypothesis: Cystatin C is a predictable marker of arterial stiffness in Chinese general population. Methods: Subjects are 748 persons (mean age, 38.8years) who attended a health checkup in Beijing, China. We measured brachial–ankle PWV (baPWV) by using an automatic oscillometric method, and the concentration of serum cystatin C was quantified. Results: The level of baPWV showed a significantly positive correlation with BMI, SBP, DBP, TG, TC, cystatin C (r = 0.251, p < 0.001), and a negative correlation with HDL-C. And when adjustment for age, BMI, and cigarette smoking, these correlations remain significantly. Conclusion: Arterial stiffness increases with an increase in serum cystatin C level in Chinese general population with normal renal function. |
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| ISSN: | 1064-1963 1525-6006 |