Contemporary Use of Coronary Physiology in Cardiology
Abstract Coronary angiography has a limited ability to predict the functional significance of intermediate coronary lesions. Hence, physiological assessment of coronary lesions, via fractional flow reserve (FFR) or instantaneous wave-free ratio (iFR), has been introduced to determine their functiona...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
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Adis, Springer Healthcare
2023-09-01
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Series: | Cardiology and Therapy |
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Online Access: | https://doi.org/10.1007/s40119-023-00329-2 |
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author | Ayman Elbadawi Ramy Sedhom Mohamed Ghoweba Abdelazeem Mohamed Etewa Waleed Kayani Faisal Rahman |
author_facet | Ayman Elbadawi Ramy Sedhom Mohamed Ghoweba Abdelazeem Mohamed Etewa Waleed Kayani Faisal Rahman |
author_sort | Ayman Elbadawi |
collection | DOAJ |
description | Abstract Coronary angiography has a limited ability to predict the functional significance of intermediate coronary lesions. Hence, physiological assessment of coronary lesions, via fractional flow reserve (FFR) or instantaneous wave-free ratio (iFR), has been introduced to determine their functional significance. An accumulating body of evidence has consolidated the role of physiology-guided revascularization, particularly among patients with stable ischemic heart disease. The use of FFR or iFR to guide decision-making in patients with stable ischemic heart disease and intermediate coronary lesions received a class I recommendation from major societal guidelines. Nevertheless, the role of coronary physiology testing is less clear among certain patients’ groups, including patients with serial coronary lesions, acute coronary syndromes, aortic stenosis, heart failure, as well as post-percutaneous coronary interventions. In this review, we aimed to discuss the utility and clinical evidence of coronary physiology (mainly FFR and iFR), with emphasis on those specific patient groups. |
first_indexed | 2024-03-09T01:14:45Z |
format | Article |
id | doaj.art-80059ee453994911b0ea968f83920c25 |
institution | Directory Open Access Journal |
issn | 2193-8261 2193-6544 |
language | English |
last_indexed | 2024-03-09T01:14:45Z |
publishDate | 2023-09-01 |
publisher | Adis, Springer Healthcare |
record_format | Article |
series | Cardiology and Therapy |
spelling | doaj.art-80059ee453994911b0ea968f83920c252023-12-10T12:35:27ZengAdis, Springer HealthcareCardiology and Therapy2193-82612193-65442023-09-0112458961410.1007/s40119-023-00329-2Contemporary Use of Coronary Physiology in CardiologyAyman Elbadawi0Ramy Sedhom1Mohamed Ghoweba2Abdelazeem Mohamed Etewa3Waleed Kayani4Faisal Rahman5Division of Cardiology, Christus Good ShepherdDepartment of Internal Medicine, Einstein Medical CentreDepartment of Internal Medicine, Christus Good ShepherdDepartment of Internal Medicine, Christus Good ShepherdSection of Cardiology, Baylor College of MedicineDivision of Cardiology, Department of Medicine, Johns Hopkins University School of MedicineAbstract Coronary angiography has a limited ability to predict the functional significance of intermediate coronary lesions. Hence, physiological assessment of coronary lesions, via fractional flow reserve (FFR) or instantaneous wave-free ratio (iFR), has been introduced to determine their functional significance. An accumulating body of evidence has consolidated the role of physiology-guided revascularization, particularly among patients with stable ischemic heart disease. The use of FFR or iFR to guide decision-making in patients with stable ischemic heart disease and intermediate coronary lesions received a class I recommendation from major societal guidelines. Nevertheless, the role of coronary physiology testing is less clear among certain patients’ groups, including patients with serial coronary lesions, acute coronary syndromes, aortic stenosis, heart failure, as well as post-percutaneous coronary interventions. In this review, we aimed to discuss the utility and clinical evidence of coronary physiology (mainly FFR and iFR), with emphasis on those specific patient groups.https://doi.org/10.1007/s40119-023-00329-2Acute coronary syndromeAortic stenosisCoronary physiologyFFRHeart failureiFR |
spellingShingle | Ayman Elbadawi Ramy Sedhom Mohamed Ghoweba Abdelazeem Mohamed Etewa Waleed Kayani Faisal Rahman Contemporary Use of Coronary Physiology in Cardiology Cardiology and Therapy Acute coronary syndrome Aortic stenosis Coronary physiology FFR Heart failure iFR |
title | Contemporary Use of Coronary Physiology in Cardiology |
title_full | Contemporary Use of Coronary Physiology in Cardiology |
title_fullStr | Contemporary Use of Coronary Physiology in Cardiology |
title_full_unstemmed | Contemporary Use of Coronary Physiology in Cardiology |
title_short | Contemporary Use of Coronary Physiology in Cardiology |
title_sort | contemporary use of coronary physiology in cardiology |
topic | Acute coronary syndrome Aortic stenosis Coronary physiology FFR Heart failure iFR |
url | https://doi.org/10.1007/s40119-023-00329-2 |
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