Contemporary Use of Coronary Physiology in Cardiology

Abstract Coronary angiography has a limited ability to predict the functional significance of intermediate coronary lesions. Hence, physiological assessment of coronary lesions, via fractional flow reserve (FFR) or instantaneous wave-free ratio (iFR), has been introduced to determine their functiona...

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Main Authors: Ayman Elbadawi, Ramy Sedhom, Mohamed Ghoweba, Abdelazeem Mohamed Etewa, Waleed Kayani, Faisal Rahman
Format: Article
Language:English
Published: Adis, Springer Healthcare 2023-09-01
Series:Cardiology and Therapy
Subjects:
Online Access:https://doi.org/10.1007/s40119-023-00329-2
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author Ayman Elbadawi
Ramy Sedhom
Mohamed Ghoweba
Abdelazeem Mohamed Etewa
Waleed Kayani
Faisal Rahman
author_facet Ayman Elbadawi
Ramy Sedhom
Mohamed Ghoweba
Abdelazeem Mohamed Etewa
Waleed Kayani
Faisal Rahman
author_sort Ayman Elbadawi
collection DOAJ
description Abstract Coronary angiography has a limited ability to predict the functional significance of intermediate coronary lesions. Hence, physiological assessment of coronary lesions, via fractional flow reserve (FFR) or instantaneous wave-free ratio (iFR), has been introduced to determine their functional significance. An accumulating body of evidence has consolidated the role of physiology-guided revascularization, particularly among patients with stable ischemic heart disease. The use of FFR or iFR to guide decision-making in patients with stable ischemic heart disease and intermediate coronary lesions received a class I recommendation from major societal guidelines. Nevertheless, the role of coronary physiology testing is less clear among certain patients’ groups, including patients with serial coronary lesions, acute coronary syndromes, aortic stenosis, heart failure, as well as post-percutaneous coronary interventions. In this review, we aimed to discuss the utility and clinical evidence of coronary physiology (mainly FFR and iFR), with emphasis on those specific patient groups.
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spelling doaj.art-80059ee453994911b0ea968f83920c252023-12-10T12:35:27ZengAdis, Springer HealthcareCardiology and Therapy2193-82612193-65442023-09-0112458961410.1007/s40119-023-00329-2Contemporary Use of Coronary Physiology in CardiologyAyman Elbadawi0Ramy Sedhom1Mohamed Ghoweba2Abdelazeem Mohamed Etewa3Waleed Kayani4Faisal Rahman5Division of Cardiology, Christus Good ShepherdDepartment of Internal Medicine, Einstein Medical CentreDepartment of Internal Medicine, Christus Good ShepherdDepartment of Internal Medicine, Christus Good ShepherdSection of Cardiology, Baylor College of MedicineDivision of Cardiology, Department of Medicine, Johns Hopkins University School of MedicineAbstract Coronary angiography has a limited ability to predict the functional significance of intermediate coronary lesions. Hence, physiological assessment of coronary lesions, via fractional flow reserve (FFR) or instantaneous wave-free ratio (iFR), has been introduced to determine their functional significance. An accumulating body of evidence has consolidated the role of physiology-guided revascularization, particularly among patients with stable ischemic heart disease. The use of FFR or iFR to guide decision-making in patients with stable ischemic heart disease and intermediate coronary lesions received a class I recommendation from major societal guidelines. Nevertheless, the role of coronary physiology testing is less clear among certain patients’ groups, including patients with serial coronary lesions, acute coronary syndromes, aortic stenosis, heart failure, as well as post-percutaneous coronary interventions. In this review, we aimed to discuss the utility and clinical evidence of coronary physiology (mainly FFR and iFR), with emphasis on those specific patient groups.https://doi.org/10.1007/s40119-023-00329-2Acute coronary syndromeAortic stenosisCoronary physiologyFFRHeart failureiFR
spellingShingle Ayman Elbadawi
Ramy Sedhom
Mohamed Ghoweba
Abdelazeem Mohamed Etewa
Waleed Kayani
Faisal Rahman
Contemporary Use of Coronary Physiology in Cardiology
Cardiology and Therapy
Acute coronary syndrome
Aortic stenosis
Coronary physiology
FFR
Heart failure
iFR
title Contemporary Use of Coronary Physiology in Cardiology
title_full Contemporary Use of Coronary Physiology in Cardiology
title_fullStr Contemporary Use of Coronary Physiology in Cardiology
title_full_unstemmed Contemporary Use of Coronary Physiology in Cardiology
title_short Contemporary Use of Coronary Physiology in Cardiology
title_sort contemporary use of coronary physiology in cardiology
topic Acute coronary syndrome
Aortic stenosis
Coronary physiology
FFR
Heart failure
iFR
url https://doi.org/10.1007/s40119-023-00329-2
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