Oral candidiasis in HIV-AIDS patients associated with CD4 T lymphocyte levels and antiretroviral therapy
Introduction: oral candidiasis is the most common opportunistic infection in HIV-infected patients, and on many occasions it is the first manifestation of the disease. Objective: determine the association between oral candidiasis, CD4 lymphocyte levels and antiretroviral treatment in HIV/AIDS pati...
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| Format: | Article |
| Language: | English |
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Editorial Ciencias Médicas
2015-05-01
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| Series: | Revista Cubana de Estomatología |
| Subjects: | |
| Online Access: | http://www.revestomatologia.sld.cu/index.php/est/article/view/785 |
| _version_ | 1818656684231360512 |
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| author | Jonathan Harris Ricardo Alejandra Del Carmen Herrera Herrera |
| author_facet | Jonathan Harris Ricardo Alejandra Del Carmen Herrera Herrera |
| author_sort | Jonathan Harris Ricardo |
| collection | DOAJ |
| description | Introduction: oral candidiasis is the most common opportunistic infection in HIV-infected patients, and on many occasions it is the first manifestation of the disease.
Objective: determine the association between oral candidiasis, CD4 lymphocyte levels and antiretroviral treatment in HIV/AIDS patients.
Methods: a descriptive cross-sectional study was conducted. The study population was 141 patients diagnosed as HIV-positive. All clinical intraoral examinations were performed by the same examiner. Data about CD4 lymphocyte levels and antiretroviral therapy were obtained from the patients’ medical records. The information was processed with the statistical package Stata v11.
Results: 66.7 % of the study population were men. Sexual transmission was the most common form of transmission (96 %). Prevalence of oral manifestations associated with HIV was 59.5 %; the most common form of the disease was pseudomembranous candidiasis (31.3 %), followed by erythematous candidiasis (4.2 %). With respect to pseudomembranous candidiasis and CD4 levels, 22 patients had CD4 values below 200 cell/mL3, and 29 were undergoing antiretroviral therapy with two drug groups: IP/INTR.
Conclusion: pseudomembranous candidiasis is highly correlated with CD4 lymphocyte levels below 200 cell/mm3. Patients under antiretroviral monotherapy presented less candidiasis than those under bitherapy. |
| first_indexed | 2024-12-17T03:29:30Z |
| format | Article |
| id | doaj.art-800690177d3d44c192e652ad52919537 |
| institution | Directory Open Access Journal |
| issn | 0034-7507 1561-297X |
| language | English |
| last_indexed | 2024-12-17T03:29:30Z |
| publishDate | 2015-05-01 |
| publisher | Editorial Ciencias Médicas |
| record_format | Article |
| series | Revista Cubana de Estomatología |
| spelling | doaj.art-800690177d3d44c192e652ad529195372022-12-21T22:05:18ZengEditorial Ciencias MédicasRevista Cubana de Estomatología0034-75071561-297X2015-05-01531914152Oral candidiasis in HIV-AIDS patients associated with CD4 T lymphocyte levels and antiretroviral therapyJonathan Harris Ricardo0Alejandra Del Carmen Herrera Herrera1Universidad del Sinú Cartagena, en colaboración con la Corporación Universitaria “Rafael Núñez”. CartagenaUniversidad de Cartagena, en colaboración con la Corporación Universitaria “Rafael Núñez”. CartagenaIntroduction: oral candidiasis is the most common opportunistic infection in HIV-infected patients, and on many occasions it is the first manifestation of the disease. Objective: determine the association between oral candidiasis, CD4 lymphocyte levels and antiretroviral treatment in HIV/AIDS patients. Methods: a descriptive cross-sectional study was conducted. The study population was 141 patients diagnosed as HIV-positive. All clinical intraoral examinations were performed by the same examiner. Data about CD4 lymphocyte levels and antiretroviral therapy were obtained from the patients’ medical records. The information was processed with the statistical package Stata v11. Results: 66.7 % of the study population were men. Sexual transmission was the most common form of transmission (96 %). Prevalence of oral manifestations associated with HIV was 59.5 %; the most common form of the disease was pseudomembranous candidiasis (31.3 %), followed by erythematous candidiasis (4.2 %). With respect to pseudomembranous candidiasis and CD4 levels, 22 patients had CD4 values below 200 cell/mL3, and 29 were undergoing antiretroviral therapy with two drug groups: IP/INTR. Conclusion: pseudomembranous candidiasis is highly correlated with CD4 lymphocyte levels below 200 cell/mm3. Patients under antiretroviral monotherapy presented less candidiasis than those under bitherapy.http://www.revestomatologia.sld.cu/index.php/est/article/view/785candidiasis bucalantígenos cd4infecciones por vih. |
| spellingShingle | Jonathan Harris Ricardo Alejandra Del Carmen Herrera Herrera Oral candidiasis in HIV-AIDS patients associated with CD4 T lymphocyte levels and antiretroviral therapy Revista Cubana de Estomatología candidiasis bucal antígenos cd4 infecciones por vih. |
| title | Oral candidiasis in HIV-AIDS patients associated with CD4 T lymphocyte levels and antiretroviral therapy |
| title_full | Oral candidiasis in HIV-AIDS patients associated with CD4 T lymphocyte levels and antiretroviral therapy |
| title_fullStr | Oral candidiasis in HIV-AIDS patients associated with CD4 T lymphocyte levels and antiretroviral therapy |
| title_full_unstemmed | Oral candidiasis in HIV-AIDS patients associated with CD4 T lymphocyte levels and antiretroviral therapy |
| title_short | Oral candidiasis in HIV-AIDS patients associated with CD4 T lymphocyte levels and antiretroviral therapy |
| title_sort | oral candidiasis in hiv aids patients associated with cd4 t lymphocyte levels and antiretroviral therapy |
| topic | candidiasis bucal antígenos cd4 infecciones por vih. |
| url | http://www.revestomatologia.sld.cu/index.php/est/article/view/785 |
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