CCL4 Deletion Accelerates Wound Healing by Improving Endothelial Cell Functions in Diabetes Mellitus

CCL4 Deletion Accelerates Wound Healing by Improving Endothelial Cell Functions in Diabetes Mellitus

Chronic inflammation in diabetes mellitus (DM) is the leading cause of non-healing wounds. Chemokine CC motif ligand 4 (CCL4) is enhanced in the circulation and in the wounds of DM patients. This study aimed to investigate the effect of endogenous CCL4 inhibition on diabetic wound healing. Endotheli...

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Bibliographic Details
Main Authors: Ting-Ting Chang, Ching Chen, Liang-Yu Lin, Jaw-Wen Chen
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biomedicines
Subjects:
chemokine CC motif ligand 4
diabetes mellitus
endothelial progenitor cells
human dermal microvascular endothelial cells
inflammation
wound healing
Online Access:https://www.mdpi.com/2227-9059/10/8/1963

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