Imaging of the Effect of Alcohol-Containing Media on the Performance of Hypromellose Hydrophilic Matrix Tablets: Comparison of Direct Compression and Regular Grades of Polymer

Imaging of the Effect of Alcohol-Containing Media on the Performance of Hypromellose Hydrophilic Matrix Tablets: Comparison of Direct Compression and Regular Grades of Polymer

As the ingestion of drug products with alcohol could have adverse effects on the release of drugs from dosage forms, it is important to understand the mechanisms underpinning the influence on drug release by evaluating the effect of alcohol-containing media on the behaviour of pharmaceutical excipie...

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Bibliographic Details
Main Authors: Nihad Mawla, Sarah Hanley, Karl Walton, Waseem Kaialy, Tariq Hussain, Adam Ward, Jonathan Brown, Barbara R. Conway, Peter Timmins, Kofi Asare-Addo
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Pharmaceutics
Subjects:
hypromellose
alcohol
dissolution
tomography
magnetic resonance imaging
tribo-electrification
Online Access:https://www.mdpi.com/1999-4923/12/9/889

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