Genetic Determinants of Neurobehavioral Responses to Caffeine Administration during Sleep Deprivation: A Randomized, Cross Over Study (NCT03859882)

Genetic Determinants of Neurobehavioral Responses to Caffeine Administration during Sleep Deprivation: A Randomized, Cross Over Study (NCT03859882)

This study investigated whether four single nucleotide polymorphisms (SNPs) moderated caffeine effects on vigilance and performance in a double-blind and crossover total sleep deprivation (TSD) protocol in 37 subjects. In caffeine (2 × 2.5 mg/kg/24 h) or placebo-controlled condition, subjects perfor...

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Bibliographic Details
Main Authors: Mégane Erblang, Fabien Sauvet, Catherine Drogou, Michaël Quiquempoix, Pascal Van Beers, Mathias Guillard, Arnaud Rabat, Aurélie Trignol, Cyprien Bourrilhon, Marie-Claire Erkel, Damien Léger, Claire Thomas, Danielle Gomez-Merino, Mounir Chennaoui
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Genes
Subjects:
genetics
caffeine
total sleep deprivation
PVT
pro-inflammatory cytokine
adenosine
Online Access:https://www.mdpi.com/2073-4425/12/4/555

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