The Neuroimmunologic Approach to Tension Type Headache and Migraine
OBJECTIVE: The immunologic studies that investigate pat- hogenesis of tension type headache are going on. Although the studies about interleukines, TNF-α, IgG, complemans and NO were reported, the parameters like MIP-1α, RANTES, eotaxin and endotelin-1 (ET-1) ha- ven’t been studied yet METHODS:...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2006-04-01
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| Series: | Türk Nöroloji Dergisi |
| Subjects: | |
| Online Access: | https://www.journalagent.com/tjn/pdfs/TJN_12_2_129_133.pdf |
| _version_ | 1828027802178289664 |
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| author | Ceyla İrkeç Hale Zeynep Batur Özlem Aksoy Hacer Doğanay |
| author_facet | Ceyla İrkeç Hale Zeynep Batur Özlem Aksoy Hacer Doğanay |
| author_sort | Ceyla İrkeç |
| collection | DOAJ |
| description | OBJECTIVE: The immunologic studies that investigate pat-
hogenesis of tension type headache are going on. Although the studies
about interleukines, TNF-α, IgG, complemans and NO were reported,
the parameters like MIP-1α, RANTES, eotaxin and endotelin-1 (ET-1) ha-
ven’t been studied yet
METHODS: The aim of our study was investigated the role of TNF-α, IL-
6, NO and MIP-1α, RANTES, eotaxin and ET-1 at the pathogenesis of
tension type headache and compared these parameters with migraine
patients.
RESULTS: The level of these parameters were measured
during headache period and headache free period at 72 patients with
tension type headache (32 of them episodic and 40 of them chronic
type), 58 patients with migraine (30 of them with aura and 28 of them
without aura) and 30 healthy patients.
CONCLUSION: It was founded that TNF-α, IL-6, NO, MIP-1α, RANTES, eotaxin
and ET-1 levels were increased at the patients with tension type headac-
he and migraine during the headache period when was compared with
control group and the patients in headache free period. These results can be thought that they are similarity in ne-
uroimmunologic reactions between tension type and and MIP-1α,
RANTES, eotaxin and ET-1 could be have a role in pathogenesis of ten-
sion type headache |
| first_indexed | 2024-04-10T13:41:20Z |
| format | Article |
| id | doaj.art-8013d14442ba45fbb5a0065ac201cbad |
| institution | Directory Open Access Journal |
| issn | 1301-062X 1309-2545 |
| language | English |
| last_indexed | 2024-04-10T13:41:20Z |
| publishDate | 2006-04-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Nöroloji Dergisi |
| spelling | doaj.art-8013d14442ba45fbb5a0065ac201cbad2023-02-15T16:11:08ZengGalenos YayineviTürk Nöroloji Dergisi1301-062X1309-25452006-04-01122129133The Neuroimmunologic Approach to Tension Type Headache and MigraineCeyla İrkeç0Hale Zeynep Batur1Özlem Aksoy2Hacer Doğanay3Department Of Neurology, Neuroimmunology Unit, Gazi University, Faculty Of Medicine, Ankara, TurkeyDepartment Of Neurology, Neuroimmunology Unit, Gazi University, Faculty Of Medicine, Ankara, TurkeyDepartment Of Neurology, Neuroimmunology Unit, Gazi University, Faculty Of Medicine, Ankara, TurkeyDepartment Of Neurology, Neuroimmunology Unit, Gazi University, Faculty Of Medicine, Ankara, TurkeyOBJECTIVE: The immunologic studies that investigate pat- hogenesis of tension type headache are going on. Although the studies about interleukines, TNF-α, IgG, complemans and NO were reported, the parameters like MIP-1α, RANTES, eotaxin and endotelin-1 (ET-1) ha- ven’t been studied yet METHODS: The aim of our study was investigated the role of TNF-α, IL- 6, NO and MIP-1α, RANTES, eotaxin and ET-1 at the pathogenesis of tension type headache and compared these parameters with migraine patients. RESULTS: The level of these parameters were measured during headache period and headache free period at 72 patients with tension type headache (32 of them episodic and 40 of them chronic type), 58 patients with migraine (30 of them with aura and 28 of them without aura) and 30 healthy patients. CONCLUSION: It was founded that TNF-α, IL-6, NO, MIP-1α, RANTES, eotaxin and ET-1 levels were increased at the patients with tension type headac- he and migraine during the headache period when was compared with control group and the patients in headache free period. These results can be thought that they are similarity in ne- uroimmunologic reactions between tension type and and MIP-1α, RANTES, eotaxin and ET-1 could be have a role in pathogenesis of ten- sion type headachehttps://www.journalagent.com/tjn/pdfs/TJN_12_2_129_133.pdfTension type headachepathophysiologycytokinechemokine |
| spellingShingle | Ceyla İrkeç Hale Zeynep Batur Özlem Aksoy Hacer Doğanay The Neuroimmunologic Approach to Tension Type Headache and Migraine Türk Nöroloji Dergisi Tension type headache pathophysiology cytokine chemokine |
| title | The Neuroimmunologic Approach to Tension Type Headache and Migraine |
| title_full | The Neuroimmunologic Approach to Tension Type Headache and Migraine |
| title_fullStr | The Neuroimmunologic Approach to Tension Type Headache and Migraine |
| title_full_unstemmed | The Neuroimmunologic Approach to Tension Type Headache and Migraine |
| title_short | The Neuroimmunologic Approach to Tension Type Headache and Migraine |
| title_sort | neuroimmunologic approach to tension type headache and migraine |
| topic | Tension type headache pathophysiology cytokine chemokine |
| url | https://www.journalagent.com/tjn/pdfs/TJN_12_2_129_133.pdf |
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