Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella
Two new 4,5-seco-caryophyllane sesquiterpenoids, rumphellaones B (1) and C (2), which were found to possess unprecedented γ-lactone moieties, were obtained from the gorgonian coral Rumphella antipathies. The structures of 1 and 2 were elucidated by spectroscopic methods and compound 2 was found to d...
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| Format: | Article |
| Language: | English |
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MDPI AG
2014-08-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/19/8/12320 |
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| author | Hsu-Ming Chung Wei-Hsien Wang Tsong-Long Hwang Jan-Jung Li Lee-Shing Fang Yang-Chang Wu Ping-Jyun Sung |
| author_facet | Hsu-Ming Chung Wei-Hsien Wang Tsong-Long Hwang Jan-Jung Li Lee-Shing Fang Yang-Chang Wu Ping-Jyun Sung |
| author_sort | Hsu-Ming Chung |
| collection | DOAJ |
| description | Two new 4,5-seco-caryophyllane sesquiterpenoids, rumphellaones B (1) and C (2), which were found to possess unprecedented γ-lactone moieties, were obtained from the gorgonian coral Rumphella antipathies. The structures of 1 and 2 were elucidated by spectroscopic methods and compound 2 was found to display modest inhibitory effects on the generation of superoxide anions and the release of elastase by human neutrophils at a concentration of 10 μg/mL |
| first_indexed | 2024-12-23T03:09:22Z |
| format | Article |
| id | doaj.art-801422db3f3f489482b4e682cebbed5b |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-23T03:09:22Z |
| publishDate | 2014-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-801422db3f3f489482b4e682cebbed5b2022-12-21T18:02:16ZengMDPI AGMolecules1420-30492014-08-01198123201232710.3390/molecules190812320molecules190812320Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from RumphellaHsu-Ming Chung0Wei-Hsien Wang1Tsong-Long Hwang2Jan-Jung Li3Lee-Shing Fang4Yang-Chang Wu5Ping-Jyun Sung6Department of Applied Chemistry, National Pingtung University, Pingtung 900, TaiwanNational Museum of Marine Biology and Aquarium, Pingtung 944, TaiwanGraduate Institute of Natural Products, Chang Gung University, Taoyuan 333, TaiwanNational Museum of Marine Biology and Aquarium, Pingtung 944, TaiwanDepartment of Sport, Health and Leisure, Cheng Shiu University, Kaohsiung 833, TaiwanSchool of Pharmacy, College of Pharmacy, China Medical University, Taichung 404, TaiwanNational Museum of Marine Biology and Aquarium, Pingtung 944, TaiwanTwo new 4,5-seco-caryophyllane sesquiterpenoids, rumphellaones B (1) and C (2), which were found to possess unprecedented γ-lactone moieties, were obtained from the gorgonian coral Rumphella antipathies. The structures of 1 and 2 were elucidated by spectroscopic methods and compound 2 was found to display modest inhibitory effects on the generation of superoxide anions and the release of elastase by human neutrophils at a concentration of 10 μg/mLhttp://www.mdpi.com/1420-3049/19/8/12320Rumphella antipathiesrumphellaones B and Ccaryophyllane-type sesquiterpenoidanti-inflammatory activity |
| spellingShingle | Hsu-Ming Chung Wei-Hsien Wang Tsong-Long Hwang Jan-Jung Li Lee-Shing Fang Yang-Chang Wu Ping-Jyun Sung Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella Molecules Rumphella antipathies rumphellaones B and C caryophyllane-type sesquiterpenoid anti-inflammatory activity |
| title | Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella |
| title_full | Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella |
| title_fullStr | Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella |
| title_full_unstemmed | Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella |
| title_short | Rumphellaones B and C, New 4,5-Seco-Caryophyllane Sesquiterpenoids from Rumphella |
| title_sort | rumphellaones b and c new 4 5 seco caryophyllane sesquiterpenoids from rumphella |
| topic | Rumphella antipathies rumphellaones B and C caryophyllane-type sesquiterpenoid anti-inflammatory activity |
| url | http://www.mdpi.com/1420-3049/19/8/12320 |
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