Src-family kinases negatively regulate NFAT signaling in resting human T cells.

Src-family kinases negatively regulate NFAT signaling in resting human T cells.

T cell signaling is required for activation of both natural and therapeutic T cells including chimeric antigen receptor (CAR) T cells. Identification of novel factors and pathways regulating T cell signaling may aid in development of effective T cell therapies. In resting human T cells, the majority...

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Bibliographic Details
Main Authors: Alan Baer, Winston Colon-Moran, Jinhua Xiang, Jack T Stapleton, Nirjal Bhattarai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5658144?pdf=render

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http://europepmc.org/articles/PMC5658144?pdf=render

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