An Efficient One Pot Procedure for Preparation of Symmetrical N,N'-Disubstituted Urea from Aromatic and Aliphatic Amines and Urea under Microwave Irradiation

A phosgene-free synthesis of symmetrical N,N'-disubstituted urea by the reaction of aromatic and aliphatic primary amines and urea promoted by  microwave irradiation in the presence of a suitable energy-transfer solvent such as N-N-dimethylacetamide is described.

Bibliographic Details
Main Authors: Mohammad S. Khajavi, Mohammad Gl Dakamin, Hassan Hazarkhani, Mostafa Hajihadi, Farzad Nikpour
Format: Article
Language:English
Published: Iranian Institute of Research and Development in Chemical Industries (IRDCI)-ACECR 2000-06-01
Series:Iranian Journal of Chemistry & Chemical Engineering
Subjects:
Online Access:http://www.ijcce.ac.ir/article_10203_4cdbfce8016c17706968d99a59c7dfc5.pdf
_version_ 1819182519059218432
author Mohammad S. Khajavi
Mohammad Gl Dakamin
Hassan Hazarkhani
Mostafa Hajihadi
Farzad Nikpour
author_facet Mohammad S. Khajavi
Mohammad Gl Dakamin
Hassan Hazarkhani
Mostafa Hajihadi
Farzad Nikpour
author_sort Mohammad S. Khajavi
collection DOAJ
description A phosgene-free synthesis of symmetrical N,N'-disubstituted urea by the reaction of aromatic and aliphatic primary amines and urea promoted by  microwave irradiation in the presence of a suitable energy-transfer solvent such as N-N-dimethylacetamide is described.
first_indexed 2024-12-22T22:47:25Z
format Article
id doaj.art-801c24f905564636ac60e9295967f80c
institution Directory Open Access Journal
issn 1021-9986
1021-9986
language English
last_indexed 2024-12-22T22:47:25Z
publishDate 2000-06-01
publisher Iranian Institute of Research and Development in Chemical Industries (IRDCI)-ACECR
record_format Article
series Iranian Journal of Chemistry & Chemical Engineering
spelling doaj.art-801c24f905564636ac60e9295967f80c2022-12-21T18:10:02ZengIranian Institute of Research and Development in Chemical Industries (IRDCI)-ACECRIranian Journal of Chemistry & Chemical Engineering1021-99861021-99862000-06-01191242810203An Efficient One Pot Procedure for Preparation of Symmetrical N,N'-Disubstituted Urea from Aromatic and Aliphatic Amines and Urea under Microwave IrradiationMohammad S. Khajavi0Mohammad Gl Dakamin1Hassan Hazarkhani2Mostafa Hajihadi3Farzad Nikpour4Department of Chemistry, Faculty of Science, Shahid Beheshti University, Department of Chemistry, Faculty of Science, Shahid Beheshti University, Tehran, I.R. IRAN, I.R. IRANDepartment of Chemistry, Faculty of Science, Shahid Beheshti University, Tehran, I.R. IRANDepartment of Chemistry, Faculty of Science, Shahid Beheshti University, Tehran, I.R. IRANDepartment of Chemistry, Faculty of Science, Shahid Beheshti University, Tehran, I.R. IRANDepartment of Chemistry, Faculty of Science, Shahid Beheshti University, Tehran, I.R. IRANA phosgene-free synthesis of symmetrical N,N'-disubstituted urea by the reaction of aromatic and aliphatic primary amines and urea promoted by  microwave irradiation in the presence of a suitable energy-transfer solvent such as N-N-dimethylacetamide is described.http://www.ijcce.ac.ir/article_10203_4cdbfce8016c17706968d99a59c7dfc5.pdfmicrowave irradiationaminesn'-disubstituted urean-dimethylacetamidesolvent free reactionurea
spellingShingle Mohammad S. Khajavi
Mohammad Gl Dakamin
Hassan Hazarkhani
Mostafa Hajihadi
Farzad Nikpour
An Efficient One Pot Procedure for Preparation of Symmetrical N,N'-Disubstituted Urea from Aromatic and Aliphatic Amines and Urea under Microwave Irradiation
Iranian Journal of Chemistry & Chemical Engineering
microwave irradiation
amines
n'-disubstituted urea
n-dimethylacetamide
solvent free reaction
urea
title An Efficient One Pot Procedure for Preparation of Symmetrical N,N'-Disubstituted Urea from Aromatic and Aliphatic Amines and Urea under Microwave Irradiation
title_full An Efficient One Pot Procedure for Preparation of Symmetrical N,N'-Disubstituted Urea from Aromatic and Aliphatic Amines and Urea under Microwave Irradiation
title_fullStr An Efficient One Pot Procedure for Preparation of Symmetrical N,N'-Disubstituted Urea from Aromatic and Aliphatic Amines and Urea under Microwave Irradiation
title_full_unstemmed An Efficient One Pot Procedure for Preparation of Symmetrical N,N'-Disubstituted Urea from Aromatic and Aliphatic Amines and Urea under Microwave Irradiation
title_short An Efficient One Pot Procedure for Preparation of Symmetrical N,N'-Disubstituted Urea from Aromatic and Aliphatic Amines and Urea under Microwave Irradiation
title_sort efficient one pot procedure for preparation of symmetrical n n disubstituted urea from aromatic and aliphatic amines and urea under microwave irradiation
topic microwave irradiation
amines
n'-disubstituted urea
n-dimethylacetamide
solvent free reaction
urea
url http://www.ijcce.ac.ir/article_10203_4cdbfce8016c17706968d99a59c7dfc5.pdf
work_keys_str_mv AT mohammadskhajavi anefficientonepotprocedureforpreparationofsymmetricalnndisubstitutedureafromaromaticandaliphaticaminesandureaundermicrowaveirradiation
AT mohammadgldakamin anefficientonepotprocedureforpreparationofsymmetricalnndisubstitutedureafromaromaticandaliphaticaminesandureaundermicrowaveirradiation
AT hassanhazarkhani anefficientonepotprocedureforpreparationofsymmetricalnndisubstitutedureafromaromaticandaliphaticaminesandureaundermicrowaveirradiation
AT mostafahajihadi anefficientonepotprocedureforpreparationofsymmetricalnndisubstitutedureafromaromaticandaliphaticaminesandureaundermicrowaveirradiation
AT farzadnikpour anefficientonepotprocedureforpreparationofsymmetricalnndisubstitutedureafromaromaticandaliphaticaminesandureaundermicrowaveirradiation
AT mohammadskhajavi efficientonepotprocedureforpreparationofsymmetricalnndisubstitutedureafromaromaticandaliphaticaminesandureaundermicrowaveirradiation
AT mohammadgldakamin efficientonepotprocedureforpreparationofsymmetricalnndisubstitutedureafromaromaticandaliphaticaminesandureaundermicrowaveirradiation
AT hassanhazarkhani efficientonepotprocedureforpreparationofsymmetricalnndisubstitutedureafromaromaticandaliphaticaminesandureaundermicrowaveirradiation
AT mostafahajihadi efficientonepotprocedureforpreparationofsymmetricalnndisubstitutedureafromaromaticandaliphaticaminesandureaundermicrowaveirradiation
AT farzadnikpour efficientonepotprocedureforpreparationofsymmetricalnndisubstitutedureafromaromaticandaliphaticaminesandureaundermicrowaveirradiation