Chondrosarcoma Arising in an Enchondroma of the Metacarpal Bone - A Case Report

Chondrosarcoma is a rare malignant tumour of proliferating cartilaginous tissue. It may arise as a primary lesion, or occur secondarily at the site of a previous benign lesion such as enchondroma . Primary chondrosarcomas are rare in the hand with a frequency of less than 0.5% to 3.2% of all chond...

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Main Authors: Honnappa Sridhar, Mysorekar Vijaya, Wilfred Clement, Chirukuri Srinivas
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2014-03-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/4139/49-%208142_E(Ra)_F(P)_PF1(Ra_P)_PF2(PAK)_PFA(AK)_V(E)_PF2(PN).pdf
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author Honnappa Sridhar
Mysorekar Vijaya
Wilfred Clement
Chirukuri Srinivas
author_facet Honnappa Sridhar
Mysorekar Vijaya
Wilfred Clement
Chirukuri Srinivas
author_sort Honnappa Sridhar
collection DOAJ
description Chondrosarcoma is a rare malignant tumour of proliferating cartilaginous tissue. It may arise as a primary lesion, or occur secondarily at the site of a previous benign lesion such as enchondroma . Primary chondrosarcomas are rare in the hand with a frequency of less than 0.5% to 3.2% of all chondrosarcomas, and are seen involving the phalanges, trapezium and trapezoid. Malignant transformation of a benign solitary enchondroma to secondary chondrosarcoma, especially in the hand, is extremely rare. We report a case, where the patient had developed a painful swelling in the 5th metacarpal bone of the right hand, 15 years back, which was diagnosed as enchondroma. Subsequently the patient presented with a 3-year history of increase in the size of the swelling at the same site, which on radiological and histopathological examination revealed malignant transformation into chondrosarcoma. We also discuss the differential diagnosis of chondrosarcoma. Keeping in mind the possibility of local recurrence and metastasis of chondrosarcoma, a ray amputation of the 4th and 5th digits of the right hand along with the mass was performed retaining the normal functioning of the hand.
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spelling doaj.art-802397b1318b461797933cf0443b9b2c2022-12-22T02:23:21ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2014-03-018314214310.7860/JCDR/2014/8142.4139Chondrosarcoma Arising in an Enchondroma of the Metacarpal Bone - A Case ReportHonnappa Sridhar0Mysorekar Vijaya1Wilfred Clement2Chirukuri Srinivas3Assistant Professor, Department of Pathology, M.S. Ramaiah Medical College, India.Professor, Department of Pathology, M.S. Ramaiah Medical College, India.Assistant Professor, Department of Pathology, M.S. Ramaiah Medical College, India. Ex- Assistant Professor, Department of Orthopaedic Oncology, M.S. Ramaiah Medical College, India.Chondrosarcoma is a rare malignant tumour of proliferating cartilaginous tissue. It may arise as a primary lesion, or occur secondarily at the site of a previous benign lesion such as enchondroma . Primary chondrosarcomas are rare in the hand with a frequency of less than 0.5% to 3.2% of all chondrosarcomas, and are seen involving the phalanges, trapezium and trapezoid. Malignant transformation of a benign solitary enchondroma to secondary chondrosarcoma, especially in the hand, is extremely rare. We report a case, where the patient had developed a painful swelling in the 5th metacarpal bone of the right hand, 15 years back, which was diagnosed as enchondroma. Subsequently the patient presented with a 3-year history of increase in the size of the swelling at the same site, which on radiological and histopathological examination revealed malignant transformation into chondrosarcoma. We also discuss the differential diagnosis of chondrosarcoma. Keeping in mind the possibility of local recurrence and metastasis of chondrosarcoma, a ray amputation of the 4th and 5th digits of the right hand along with the mass was performed retaining the normal functioning of the hand.https://jcdr.net/articles/PDF/4139/49-%208142_E(Ra)_F(P)_PF1(Ra_P)_PF2(PAK)_PFA(AK)_V(E)_PF2(PN).pdfenchondromachondrosarcomametacarpalmalignant transformationamputation
spellingShingle Honnappa Sridhar
Mysorekar Vijaya
Wilfred Clement
Chirukuri Srinivas
Chondrosarcoma Arising in an Enchondroma of the Metacarpal Bone - A Case Report
Journal of Clinical and Diagnostic Research
enchondroma
chondrosarcoma
metacarpal
malignant transformation
amputation
title Chondrosarcoma Arising in an Enchondroma of the Metacarpal Bone - A Case Report
title_full Chondrosarcoma Arising in an Enchondroma of the Metacarpal Bone - A Case Report
title_fullStr Chondrosarcoma Arising in an Enchondroma of the Metacarpal Bone - A Case Report
title_full_unstemmed Chondrosarcoma Arising in an Enchondroma of the Metacarpal Bone - A Case Report
title_short Chondrosarcoma Arising in an Enchondroma of the Metacarpal Bone - A Case Report
title_sort chondrosarcoma arising in an enchondroma of the metacarpal bone a case report
topic enchondroma
chondrosarcoma
metacarpal
malignant transformation
amputation
url https://jcdr.net/articles/PDF/4139/49-%208142_E(Ra)_F(P)_PF1(Ra_P)_PF2(PAK)_PFA(AK)_V(E)_PF2(PN).pdf
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AT mysorekarvijaya chondrosarcomaarisinginanenchondromaofthemetacarpalboneacasereport
AT wilfredclement chondrosarcomaarisinginanenchondromaofthemetacarpalboneacasereport
AT chirukurisrinivas chondrosarcomaarisinginanenchondromaofthemetacarpalboneacasereport