Lactylation, a Novel Metabolic Reprogramming Code: Current Status and Prospects

Lactylation, a Novel Metabolic Reprogramming Code: Current Status and Prospects

Lactate is an end product of glycolysis. As a critical energy source for mitochondrial respiration, lactate also acts as a precursor of gluconeogenesis and a signaling molecule. We briefly summarize emerging concepts regarding lactate metabolism, such as the lactate shuttle, lactate homeostasis, and...

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Bibliographic Details
Main Authors: An-Na Chen, Yan Luo, Yu-Han Yang, Jian-Tao Fu, Xiu-Mei Geng, Jun-Ping Shi, Jin Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
lactate
lactylation
macrophage
epigenetic
posttranslational modification
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.688910/full

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