Genome-wide association studies of global Mycobacterium tuberculosis resistance to 13 antimicrobials in 10,228 genomes identify new resistance mechanisms.
The emergence of drug-resistant tuberculosis is a major global public health concern that threatens the ability to control the disease. Whole-genome sequencing as a tool to rapidly diagnose resistant infections can transform patient treatment and clinical practice. While resistance mechanisms are we...
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Format: | Article |
Language: | English |
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Public Library of Science (PLoS)
2022-08-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3001755 |