Summary: | Creatine is a non-proteinogenic amino acid available from various animal-based foods or synthesized endogenously in the human body. A number of recent population-based studies demonstrate a lower-than-expected dietary creatine intake across age- and gender-specific cohorts, with low creatine consumption accompanied by various health risks. Those studies suggest that the general public may benefit from creatine to prevent and manage various health conditions or to ensure advanced growth. Favorable safety and promising impact of supplemental creatine on human well-being and functioning emanated from plenty of small-sampled interventional studies perhaps suggest a need for recommending creatine to the general public. In this opinion paper, I have outlined the possible rationales for endorsing supplemental creatine ubiquitously, and discussed opportunities and challenges for population-wide creatine use.
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