Impact of weight change after quitting cigarettes on all-cause and cause-specific mortality in middle-aged male smokers: national health screening cohort study
Background We aimed to investigate the association between weight change after smoking cessation and the risk of all-cause and cause-specific mortality among middle-aged male smokers. Methods We conducted a prospective cohort study using the National Health Insurance Service National Health Scree...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
European Publishing
2018-03-01
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| Series: | Tobacco Induced Diseases |
| Subjects: | |
| Online Access: | http://www.journalssystem.com/tid/Impact-of-weight-change-after-quitting-cigarettes-on-all-cause-and-cause-specific,84073,0,2.html |
| _version_ | 1818569172079083520 |
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| author | Kyuwoong Kim Seulggie Choi Mi Hee Cho Ji Hye Jun Jooyoung Chang Sung Min Kim Kiheon Lee Sang Min Park |
| author_facet | Kyuwoong Kim Seulggie Choi Mi Hee Cho Ji Hye Jun Jooyoung Chang Sung Min Kim Kiheon Lee Sang Min Park |
| author_sort | Kyuwoong Kim |
| collection | DOAJ |
| description | Background
We aimed to investigate the
association between weight change after smoking cessation and the risk of
all-cause and cause-specific mortality among middle-aged male smokers.
Methods
We conducted a
prospective cohort study using the National Health Insurance Service National
Health Screening Cohort (NHIS-HealS) database. Male Participants (n=102,403)
without critical conditions aged between 40 and 79 at baseline who underwent
biennial health examination were included in this study. Participants were
categorized into continued smokers, recent quitters (within 4 years), long-term
quitters (more than 4 years), and never-smokers based on the self-reported
smoking status. Weight change was determined by the change of Body Mass Index
(BMI) between the first (2002-2003) and second (2004-2005) health examination
records. We followed patients from January 1, 2006 to December, 31, 2013. To
assess the risk of all-cause, cancer, cardiovascular disease (CVD) mortality,
and non-cancer, non-CVD mortality according to smoking cessation and weight
change, we computed Hazard Ratio (HR) and 95% Confidence Interval (95% CI)
using Cox proportional hazard models.
Results
Severity of
weight gain was more prevalent among recent quitters compared to long-term
quitters. After adjusting for covariates and weight change, both recent
quitters (HR:0.74; 95% CI: 0.63-0.87) and long-term quitters (HR:0.53; 95%
CI:0.45-0.61) had decreased risk of all-cause mortality compared to continued
smokers. Similarly, both recent and long-term quitters had decreased risk of
cancer, CVD, non-cancer, and non-CVD death regardless of weight change
following smoking cessation. Compared to continued smokers, non-smokers also
had a lower risk of overall and cause-specific death.
Conclusions
Post-cessation weight change
did not modify the protective association of smoking cessation with reduced
risk of all-cause and cause-specific death. From a public health perspective,
smoking cessation program may contribute to reducing risk of death in
middle-aged male smokers despite the concern on weight change after quitting
smoking. |
| first_indexed | 2024-12-14T06:44:38Z |
| format | Article |
| id | doaj.art-80320776b1ba44faa6928d0628970605 |
| institution | Directory Open Access Journal |
| issn | 1617-9625 |
| language | English |
| last_indexed | 2024-12-14T06:44:38Z |
| publishDate | 2018-03-01 |
| publisher | European Publishing |
| record_format | Article |
| series | Tobacco Induced Diseases |
| spelling | doaj.art-80320776b1ba44faa6928d06289706052022-12-21T23:13:07ZengEuropean PublishingTobacco Induced Diseases1617-96252018-03-0116110.18332/tid/8407384073Impact of weight change after quitting cigarettes on all-cause and cause-specific mortality in middle-aged male smokers: national health screening cohort studyKyuwoong Kim0Seulggie Choi1Mi Hee Cho2Ji Hye Jun3Jooyoung Chang4Sung Min Kim5Kiheon Lee6Sang Min Park7Seoul National University, Korea, Republic ofSeoul National University, Department of Biomedical Sciences, Korea, Republic ofSeoul National University Hospital, Department of Family Medicine, Korea, Republic ofSeoul National University Bundang Hospital, Department of Family Medicine, Korea, Republic ofSeoul National University, College of Medicine, Korea, Republic ofSeoul National University, Department of Biomedical Sciences, Korea, Republic ofSeoul National University Bundang Hospital, Department of Family Medicine, Korea, Republic ofSeoul National University Hospital, Department of Family Medicine, Korea, Republic ofBackground We aimed to investigate the association between weight change after smoking cessation and the risk of all-cause and cause-specific mortality among middle-aged male smokers. Methods We conducted a prospective cohort study using the National Health Insurance Service National Health Screening Cohort (NHIS-HealS) database. Male Participants (n=102,403) without critical conditions aged between 40 and 79 at baseline who underwent biennial health examination were included in this study. Participants were categorized into continued smokers, recent quitters (within 4 years), long-term quitters (more than 4 years), and never-smokers based on the self-reported smoking status. Weight change was determined by the change of Body Mass Index (BMI) between the first (2002-2003) and second (2004-2005) health examination records. We followed patients from January 1, 2006 to December, 31, 2013. To assess the risk of all-cause, cancer, cardiovascular disease (CVD) mortality, and non-cancer, non-CVD mortality according to smoking cessation and weight change, we computed Hazard Ratio (HR) and 95% Confidence Interval (95% CI) using Cox proportional hazard models. Results Severity of weight gain was more prevalent among recent quitters compared to long-term quitters. After adjusting for covariates and weight change, both recent quitters (HR:0.74; 95% CI: 0.63-0.87) and long-term quitters (HR:0.53; 95% CI:0.45-0.61) had decreased risk of all-cause mortality compared to continued smokers. Similarly, both recent and long-term quitters had decreased risk of cancer, CVD, non-cancer, and non-CVD death regardless of weight change following smoking cessation. Compared to continued smokers, non-smokers also had a lower risk of overall and cause-specific death. Conclusions Post-cessation weight change did not modify the protective association of smoking cessation with reduced risk of all-cause and cause-specific death. From a public health perspective, smoking cessation program may contribute to reducing risk of death in middle-aged male smokers despite the concern on weight change after quitting smoking.http://www.journalssystem.com/tid/Impact-of-weight-change-after-quitting-cigarettes-on-all-cause-and-cause-specific,84073,0,2.htmlWCTOH |
| spellingShingle | Kyuwoong Kim Seulggie Choi Mi Hee Cho Ji Hye Jun Jooyoung Chang Sung Min Kim Kiheon Lee Sang Min Park Impact of weight change after quitting cigarettes on all-cause and cause-specific mortality in middle-aged male smokers: national health screening cohort study Tobacco Induced Diseases WCTOH |
| title | Impact of weight change after quitting cigarettes on all-cause and cause-specific mortality in middle-aged male smokers: national health screening cohort study |
| title_full | Impact of weight change after quitting cigarettes on all-cause and cause-specific mortality in middle-aged male smokers: national health screening cohort study |
| title_fullStr | Impact of weight change after quitting cigarettes on all-cause and cause-specific mortality in middle-aged male smokers: national health screening cohort study |
| title_full_unstemmed | Impact of weight change after quitting cigarettes on all-cause and cause-specific mortality in middle-aged male smokers: national health screening cohort study |
| title_short | Impact of weight change after quitting cigarettes on all-cause and cause-specific mortality in middle-aged male smokers: national health screening cohort study |
| title_sort | impact of weight change after quitting cigarettes on all cause and cause specific mortality in middle aged male smokers national health screening cohort study |
| topic | WCTOH |
| url | http://www.journalssystem.com/tid/Impact-of-weight-change-after-quitting-cigarettes-on-all-cause-and-cause-specific,84073,0,2.html |
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