Acute Kidney Injury in the Patient with Cancer

Over the last three decades, advancements in the diagnosis, treatment, and supportive care of patients with cancer have significantly improved their overall survival. However, these advancements have also led to a higher rate of cancer-related complications. Acute kidney injury (AKI) and chronic kid...

Full description

Bibliographic Details
Main Authors: Alejandro Meraz-Munoz, Amit Langote, Kenar D. Jhaveri, Hassane Izzedine, Prakash Gudsoorkar
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/11/4/611
_version_ 1827696428083838976
author Alejandro Meraz-Munoz
Amit Langote
Kenar D. Jhaveri
Hassane Izzedine
Prakash Gudsoorkar
author_facet Alejandro Meraz-Munoz
Amit Langote
Kenar D. Jhaveri
Hassane Izzedine
Prakash Gudsoorkar
author_sort Alejandro Meraz-Munoz
collection DOAJ
description Over the last three decades, advancements in the diagnosis, treatment, and supportive care of patients with cancer have significantly improved their overall survival. However, these advancements have also led to a higher rate of cancer-related complications. Acute kidney injury (AKI) and chronic kidney disease (CKD) are highly prevalent in patients with cancer, and they are associated with an increased risk of all-cause mortality. This bidirectional interplay between cancer and kidney, termed “the kidney–cancer connection” has become a very active area of research. This review aims to provide an overview of some of the most common causes of AKI in patients with cancer. Cancer therapy-associated AKI is beyond the scope of this review and will be discussed separately.
first_indexed 2024-03-10T12:48:27Z
format Article
id doaj.art-80320b0916594dd3a17af07e104e40ff
institution Directory Open Access Journal
issn 2075-4418
language English
last_indexed 2024-03-10T12:48:27Z
publishDate 2021-03-01
publisher MDPI AG
record_format Article
series Diagnostics
spelling doaj.art-80320b0916594dd3a17af07e104e40ff2023-11-21T13:18:54ZengMDPI AGDiagnostics2075-44182021-03-0111461110.3390/diagnostics11040611Acute Kidney Injury in the Patient with CancerAlejandro Meraz-Munoz0Amit Langote1Kenar D. Jhaveri2Hassane Izzedine3Prakash Gudsoorkar4Division of Nephrology, Department of Medicine, St Michael’s Hospital, Toronto, ON M5B 1W8, CanadaConsultant Nephrologist, Apollo Hospital, Navi Mumbai, Maharashtra 400614, IndiaDivision of Kidney Diseases and Hypertension, Donald and Barbara Zucker School of Medicine, Great Neck, NY 11021, USADepartment of Nephrology, Peupliers Private Hospital, Ramsay Générale de Santé, 75013 Paris, FranceDivision of Nephrology & Kidney Clinical Advancement, Research & Education Program, University of Cincinnati, Cincinnati, OH 45267, USAOver the last three decades, advancements in the diagnosis, treatment, and supportive care of patients with cancer have significantly improved their overall survival. However, these advancements have also led to a higher rate of cancer-related complications. Acute kidney injury (AKI) and chronic kidney disease (CKD) are highly prevalent in patients with cancer, and they are associated with an increased risk of all-cause mortality. This bidirectional interplay between cancer and kidney, termed “the kidney–cancer connection” has become a very active area of research. This review aims to provide an overview of some of the most common causes of AKI in patients with cancer. Cancer therapy-associated AKI is beyond the scope of this review and will be discussed separately.https://www.mdpi.com/2075-4418/11/4/611acute kidney injury (AKI)kidney replacement therapy (KRT)thrombotic microangiopathy (TMA)hematopoietic stem cell transplant (HSCT)tumor lysis syndrome (TLS)
spellingShingle Alejandro Meraz-Munoz
Amit Langote
Kenar D. Jhaveri
Hassane Izzedine
Prakash Gudsoorkar
Acute Kidney Injury in the Patient with Cancer
Diagnostics
acute kidney injury (AKI)
kidney replacement therapy (KRT)
thrombotic microangiopathy (TMA)
hematopoietic stem cell transplant (HSCT)
tumor lysis syndrome (TLS)
title Acute Kidney Injury in the Patient with Cancer
title_full Acute Kidney Injury in the Patient with Cancer
title_fullStr Acute Kidney Injury in the Patient with Cancer
title_full_unstemmed Acute Kidney Injury in the Patient with Cancer
title_short Acute Kidney Injury in the Patient with Cancer
title_sort acute kidney injury in the patient with cancer
topic acute kidney injury (AKI)
kidney replacement therapy (KRT)
thrombotic microangiopathy (TMA)
hematopoietic stem cell transplant (HSCT)
tumor lysis syndrome (TLS)
url https://www.mdpi.com/2075-4418/11/4/611
work_keys_str_mv AT alejandromerazmunoz acutekidneyinjuryinthepatientwithcancer
AT amitlangote acutekidneyinjuryinthepatientwithcancer
AT kenardjhaveri acutekidneyinjuryinthepatientwithcancer
AT hassaneizzedine acutekidneyinjuryinthepatientwithcancer
AT prakashgudsoorkar acutekidneyinjuryinthepatientwithcancer