Polycaprolactone/Amino-β-Cyclodextrin Inclusion Complex Prepared by an Electrospinning Technique
Electrospun scaffolds of neat poly-ε-caprolactone (PCL), poly-ε-caprolactone/β-cyclodextrin inclusion complex (PCL/β-CD) and poly-ε-caprolactone amino derivative inclusion complex (PCL/β-CD-NH2) were prepared by the electrospinning technique. The obtained mats were analyzed by a theoretical model us...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2016-11-01
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| Series: | Polymers |
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| Online Access: | http://www.mdpi.com/2073-4360/8/11/395 |
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| author | Edgar Moyers-Montoya Perla García-Casillas Claudia Vargas-Requena René Escobedo-González Santos-Adriana Martel-Estrada Carlos A. Martínez-Pérez |
| author_facet | Edgar Moyers-Montoya Perla García-Casillas Claudia Vargas-Requena René Escobedo-González Santos-Adriana Martel-Estrada Carlos A. Martínez-Pérez |
| author_sort | Edgar Moyers-Montoya |
| collection | DOAJ |
| description | Electrospun scaffolds of neat poly-ε-caprolactone (PCL), poly-ε-caprolactone/β-cyclodextrin inclusion complex (PCL/β-CD) and poly-ε-caprolactone amino derivative inclusion complex (PCL/β-CD-NH2) were prepared by the electrospinning technique. The obtained mats were analyzed by a theoretical model using the Hartree–Fock method with an STO-3G basis set, and characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), Fourier transform infrared spectroscopy-attenuated total reflectance (FTIR-ATR), differential scanning calorimetry (DSC), confocal-Raman spectroscopy, proton nuclear magnetic resonance (1HNMR) and contact angle measure (CA). Different mixtures of solvents, such as dimethylformamide (DMF)-tetrahydrofuran (THF), dichlormethane (DCM)-dimethyl sulfoxide (DMSO) and 2,2,2-Trifluoroethanol (TFE), were tested in the fiber preparation. The results indicate that electrospun nanofibers have a pseudorotaxane structure and when it was prepared using a 2,2,2-Trifluoroethanol (TFE) as solvent, the nanofibers were electrospun well and, with the other solvents, fibers present defects such as molten fibers and bead-like defects into the fiber structure. This work provides insights into the design of PCL/β-CD-NH2 based scaffolds that could have applications in the biomedical field. |
| first_indexed | 2024-04-12T16:58:08Z |
| format | Article |
| id | doaj.art-80341de0617849de863894f5d63ada10 |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-04-12T16:58:08Z |
| publishDate | 2016-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-80341de0617849de863894f5d63ada102022-12-22T03:24:09ZengMDPI AGPolymers2073-43602016-11-0181139510.3390/polym8110395polym8110395Polycaprolactone/Amino-β-Cyclodextrin Inclusion Complex Prepared by an Electrospinning TechniqueEdgar Moyers-Montoya0Perla García-Casillas1Claudia Vargas-Requena2René Escobedo-González3Santos-Adriana Martel-Estrada4Carlos A. Martínez-Pérez5Instituto de Ingeniería y Tecnología, Universidad Autónoma de Ciudad Juárez, Ave. Del Charro 450 Norte, Ciudad Juárez 32310, MexicoInstituto de Ingeniería y Tecnología, Universidad Autónoma de Ciudad Juárez, Ave. Del Charro 450 Norte, Ciudad Juárez 32310, MexicoInstituto de Ciencias Biomédicas, Universidad Autónoma de Ciudad Juárez, Henry Dunant #4600, Ciudad Juárez 32310, MexicoDepartamento de Ciencias Químicas, Universidad Autónoma de México, Campo 1, Av. 1 de Mayo S/N, Colonia Santa María las Torres, Cuautitlán Izcalli 54714, MexicoInstituto de Diseño y Arte. Universidad Autónoma de Ciudad Juárez, Ave. Del Charro 450 Norte, Ciudad Juárez 32310, MexicoInstituto de Ingeniería y Tecnología, Universidad Autónoma de Ciudad Juárez, Ave. Del Charro 450 Norte, Ciudad Juárez 32310, MexicoElectrospun scaffolds of neat poly-ε-caprolactone (PCL), poly-ε-caprolactone/β-cyclodextrin inclusion complex (PCL/β-CD) and poly-ε-caprolactone amino derivative inclusion complex (PCL/β-CD-NH2) were prepared by the electrospinning technique. The obtained mats were analyzed by a theoretical model using the Hartree–Fock method with an STO-3G basis set, and characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), Fourier transform infrared spectroscopy-attenuated total reflectance (FTIR-ATR), differential scanning calorimetry (DSC), confocal-Raman spectroscopy, proton nuclear magnetic resonance (1HNMR) and contact angle measure (CA). Different mixtures of solvents, such as dimethylformamide (DMF)-tetrahydrofuran (THF), dichlormethane (DCM)-dimethyl sulfoxide (DMSO) and 2,2,2-Trifluoroethanol (TFE), were tested in the fiber preparation. The results indicate that electrospun nanofibers have a pseudorotaxane structure and when it was prepared using a 2,2,2-Trifluoroethanol (TFE) as solvent, the nanofibers were electrospun well and, with the other solvents, fibers present defects such as molten fibers and bead-like defects into the fiber structure. This work provides insights into the design of PCL/β-CD-NH2 based scaffolds that could have applications in the biomedical field.http://www.mdpi.com/2073-4360/8/11/395electro-spinningfibersfunctional composites |
| spellingShingle | Edgar Moyers-Montoya Perla García-Casillas Claudia Vargas-Requena René Escobedo-González Santos-Adriana Martel-Estrada Carlos A. Martínez-Pérez Polycaprolactone/Amino-β-Cyclodextrin Inclusion Complex Prepared by an Electrospinning Technique Polymers electro-spinning fibers functional composites |
| title | Polycaprolactone/Amino-β-Cyclodextrin Inclusion Complex Prepared by an Electrospinning Technique |
| title_full | Polycaprolactone/Amino-β-Cyclodextrin Inclusion Complex Prepared by an Electrospinning Technique |
| title_fullStr | Polycaprolactone/Amino-β-Cyclodextrin Inclusion Complex Prepared by an Electrospinning Technique |
| title_full_unstemmed | Polycaprolactone/Amino-β-Cyclodextrin Inclusion Complex Prepared by an Electrospinning Technique |
| title_short | Polycaprolactone/Amino-β-Cyclodextrin Inclusion Complex Prepared by an Electrospinning Technique |
| title_sort | polycaprolactone amino β cyclodextrin inclusion complex prepared by an electrospinning technique |
| topic | electro-spinning fibers functional composites |
| url | http://www.mdpi.com/2073-4360/8/11/395 |
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