Methylenetetrahydrofolate Reductase Gene C677T and A1298C Polymorphic Sequence Variations Influences the Susceptibility to Chronic Myeloid Leukemia in Kashmiri Population

Methylenetetrahydrofolate Reductase Gene C677T and A1298C Polymorphic Sequence Variations Influences the Susceptibility to Chronic Myeloid Leukemia in Kashmiri Population

Background: Methylenetetrahydrofolate reductase (MTHFR) gene is a crucial regulator of folate metabolism and its two prominent polymorphic variants C677T and A1298C lead to decreased MTHFR enzyme activity.Aim of the Study: We planned this case–control study based on numerous studies supporting the a...

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Bibliographic Details
Main Authors: Shahid M. Baba, Zafar A. Shah, Khushboo Javaid, Arshad A. Pandith, Javeed Rasool, Sajad A. Geelani, Rafia A. Baba, Shajrul Amin, Gul Mohammad
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Oncology
Subjects:
MTHFR
CML
BCR-ABL
PCR
Kashmir
India
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00612/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00612/full

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