Tobacco Exposure and Complications in Conservative Laryngeal Surgery
Smoking is an important risk factor in the development of head and neck cancer. However, little is known about its effects on postoperative complications in head and neck cancer surgery. We performed a retrospective analysis on 535 consecutive laryngeal cancer patients submitted to open partial lary...
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| Format: | Article |
| Language: | English |
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MDPI AG
2014-08-01
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| Series: | Cancers |
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| Online Access: | http://www.mdpi.com/2072-6694/6/3/1727 |
| _version_ | 1797723197807788032 |
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| author | Francesca Romana Fiorini Alberto Deganello Guglielmo Larotonda Giuditta Mannelli Oreste Gallo |
| author_facet | Francesca Romana Fiorini Alberto Deganello Guglielmo Larotonda Giuditta Mannelli Oreste Gallo |
| author_sort | Francesca Romana Fiorini |
| collection | DOAJ |
| description | Smoking is an important risk factor in the development of head and neck cancer. However, little is known about its effects on postoperative complications in head and neck cancer surgery. We performed a retrospective analysis on 535 consecutive laryngeal cancer patients submitted to open partial laryngectomy at the Otolaryngology-Head and Neck Surgery Department of Florence University to evaluate a possible correlation between smoking and surgical complications. Patients were grouped in non smokers and smokers and evaluated for airway, swallowing, local and fistula complications by multivariate analysis: 507 (95%) patients were smokers, 69% presented supraglottic, 30% glottic and 1% transglottic cancer. The most common operation was supraglottic horizontal laryngectomy in 58%, followed by supracricoid partial laryngectomy in 27% and frontolateral hemilaryngectomy in 15% of cases. The incidence of overall complications was 30%, airway complications representing the most frequent (14%), followed by swallowing (7%), local (6%) and fistula complications (3%). Smokers developed more local complications (p = 0.05, univariate, p = 0.04, multivariate analysis) and pharyngocutaneous fistula (p = 0.01, univariate, p = 0.03, multivariate analysis). |
| first_indexed | 2024-03-12T09:59:26Z |
| format | Article |
| id | doaj.art-80372877d43040a7bafbdfa6c26c6efb |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-12T09:59:26Z |
| publishDate | 2014-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-80372877d43040a7bafbdfa6c26c6efb2023-09-02T11:52:12ZengMDPI AGCancers2072-66942014-08-01631727173510.3390/cancers6031727cancers6031727Tobacco Exposure and Complications in Conservative Laryngeal SurgeryFrancesca Romana Fiorini0Alberto Deganello1Guglielmo Larotonda2Giuditta Mannelli3Oreste Gallo4Academic Clinic of Otolaryngology-Head and Neck Surgery, University of Florence, Via Largo Brambilla 3, 50134 Florence, ItalyAcademic Clinic of Otolaryngology-Head and Neck Surgery, University of Florence, Via Largo Brambilla 3, 50134 Florence, ItalyAcademic Clinic of Otolaryngology-Head and Neck Surgery, University of Florence, Via Largo Brambilla 3, 50134 Florence, ItalyAcademic Clinic of Otolaryngology-Head and Neck Surgery, University of Florence, Via Largo Brambilla 3, 50134 Florence, ItalyAcademic Clinic of Otolaryngology-Head and Neck Surgery, University of Florence, Via Largo Brambilla 3, 50134 Florence, ItalySmoking is an important risk factor in the development of head and neck cancer. However, little is known about its effects on postoperative complications in head and neck cancer surgery. We performed a retrospective analysis on 535 consecutive laryngeal cancer patients submitted to open partial laryngectomy at the Otolaryngology-Head and Neck Surgery Department of Florence University to evaluate a possible correlation between smoking and surgical complications. Patients were grouped in non smokers and smokers and evaluated for airway, swallowing, local and fistula complications by multivariate analysis: 507 (95%) patients were smokers, 69% presented supraglottic, 30% glottic and 1% transglottic cancer. The most common operation was supraglottic horizontal laryngectomy in 58%, followed by supracricoid partial laryngectomy in 27% and frontolateral hemilaryngectomy in 15% of cases. The incidence of overall complications was 30%, airway complications representing the most frequent (14%), followed by swallowing (7%), local (6%) and fistula complications (3%). Smokers developed more local complications (p = 0.05, univariate, p = 0.04, multivariate analysis) and pharyngocutaneous fistula (p = 0.01, univariate, p = 0.03, multivariate analysis).http://www.mdpi.com/2072-6694/6/3/1727head and neck cancerpostoperative complicationssmoking status |
| spellingShingle | Francesca Romana Fiorini Alberto Deganello Guglielmo Larotonda Giuditta Mannelli Oreste Gallo Tobacco Exposure and Complications in Conservative Laryngeal Surgery Cancers head and neck cancer postoperative complications smoking status |
| title | Tobacco Exposure and Complications in Conservative Laryngeal Surgery |
| title_full | Tobacco Exposure and Complications in Conservative Laryngeal Surgery |
| title_fullStr | Tobacco Exposure and Complications in Conservative Laryngeal Surgery |
| title_full_unstemmed | Tobacco Exposure and Complications in Conservative Laryngeal Surgery |
| title_short | Tobacco Exposure and Complications in Conservative Laryngeal Surgery |
| title_sort | tobacco exposure and complications in conservative laryngeal surgery |
| topic | head and neck cancer postoperative complications smoking status |
| url | http://www.mdpi.com/2072-6694/6/3/1727 |
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