Plant-derived natural compounds in the treatment of arsenic-induced toxicity
Arsenic toxicity, imposed mainly by arsenic-contaminated groundwater, is considered a critical threat to global communal health, as there is no specific and proven conventional therapy for chronic arsenic toxicity, i.e., arsenicosis, which is an insidious global public health menace affecting 50 cou...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Asian Pacific Journal of Tropical Biomedicine |
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| Online Access: | http://www.apjtb.org/article.asp?issn=2221-1691;year=2023;volume=13;issue=9;spage=369;epage=377;aulast=Bhattacharya |
| _version_ | 1797649574221840384 |
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| author | Sanjib Bhattacharya |
| author_facet | Sanjib Bhattacharya |
| author_sort | Sanjib Bhattacharya |
| collection | DOAJ |
| description | Arsenic toxicity, imposed mainly by arsenic-contaminated groundwater, is considered a critical threat to global communal health, as there is no specific and proven conventional therapy for chronic arsenic toxicity, i.e., arsenicosis, which is an insidious global public health menace affecting 50 countries. Alternative options should, therefore, be explored for the mitigation of arsenicosis. Literature survey reveals several natural compounds from plants possess significant protective efficacy against arsenic toxicity in chiefly preclinical and few clinical investigations. The studies on the ameliorative effects of plant-derived natural compounds against arsenic toxicity published in the last 25 years are collated. Forty-eight plant-based natural compounds possess alleviative effects on experimental arsenic-induced toxicity in animals, six of which have been reported to be clinically effective in humans. A potential nutraceutical or therapeutic candidate against arsenicosis for humans may thus be developed with the help of recent advancements in research in this area, along with the currently available treatments. |
| first_indexed | 2024-03-11T15:49:03Z |
| format | Article |
| id | doaj.art-803bab9619b1455485e5a6aa1e1c0121 |
| institution | Directory Open Access Journal |
| issn | 2221-1691 2588-9222 |
| language | English |
| last_indexed | 2024-03-11T15:49:03Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Pacific Journal of Tropical Biomedicine |
| spelling | doaj.art-803bab9619b1455485e5a6aa1e1c01212023-10-26T05:33:09ZengWolters Kluwer Medknow PublicationsAsian Pacific Journal of Tropical Biomedicine2221-16912588-92222023-01-0113936937710.4103/2221-1691.385567Plant-derived natural compounds in the treatment of arsenic-induced toxicitySanjib BhattacharyaArsenic toxicity, imposed mainly by arsenic-contaminated groundwater, is considered a critical threat to global communal health, as there is no specific and proven conventional therapy for chronic arsenic toxicity, i.e., arsenicosis, which is an insidious global public health menace affecting 50 countries. Alternative options should, therefore, be explored for the mitigation of arsenicosis. Literature survey reveals several natural compounds from plants possess significant protective efficacy against arsenic toxicity in chiefly preclinical and few clinical investigations. The studies on the ameliorative effects of plant-derived natural compounds against arsenic toxicity published in the last 25 years are collated. Forty-eight plant-based natural compounds possess alleviative effects on experimental arsenic-induced toxicity in animals, six of which have been reported to be clinically effective in humans. A potential nutraceutical or therapeutic candidate against arsenicosis for humans may thus be developed with the help of recent advancements in research in this area, along with the currently available treatments.http://www.apjtb.org/article.asp?issn=2221-1691;year=2023;volume=13;issue=9;spage=369;epage=377;aulast=Bhattacharyaarsenic toxicity; arsenicosis; natural compounds; vitamins |
| spellingShingle | Sanjib Bhattacharya Plant-derived natural compounds in the treatment of arsenic-induced toxicity Asian Pacific Journal of Tropical Biomedicine arsenic toxicity; arsenicosis; natural compounds; vitamins |
| title | Plant-derived natural compounds in the treatment of arsenic-induced toxicity |
| title_full | Plant-derived natural compounds in the treatment of arsenic-induced toxicity |
| title_fullStr | Plant-derived natural compounds in the treatment of arsenic-induced toxicity |
| title_full_unstemmed | Plant-derived natural compounds in the treatment of arsenic-induced toxicity |
| title_short | Plant-derived natural compounds in the treatment of arsenic-induced toxicity |
| title_sort | plant derived natural compounds in the treatment of arsenic induced toxicity |
| topic | arsenic toxicity; arsenicosis; natural compounds; vitamins |
| url | http://www.apjtb.org/article.asp?issn=2221-1691;year=2023;volume=13;issue=9;spage=369;epage=377;aulast=Bhattacharya |
| work_keys_str_mv | AT sanjibbhattacharya plantderivednaturalcompoundsinthetreatmentofarsenicinducedtoxicity |