Neonatal corticosterone administration increases p27-positive Sertoli cell number and decreases Sertoli cell number in the testes of mice at prepuberty

Neonatal corticosterone administration increases p27-positive Sertoli cell number and decreases Sertoli cell number in the testes of mice at prepuberty

Abstract Cortisol and corticosterone (CORT) are steroid, antistress hormones and one of the glucocorticoids in humans and animals, respectively. This study evaluated the effects of CORT administration on the male reproductive system in early life stages. CORT was subcutaneously injected at 0.36 (low...

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Bibliographic Details
Main Authors: Hidenobu Miyaso, Kaiya Takano, Kenta Nagahori, Zhong-Lian Li, Shinichi Kawata, Miyuki Kuramasu, Yuki Ogawa, Hirotaka Yoshioka, Yoshiharu Matsuno, Satoshi Yokota, Masahiro Itoh
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-23695-8

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