The evolution and functional divergence of the histone H2B family in plants.
Chromatin regulation of eukaryotic genomes depends on the formation of nucleosome complexes between histone proteins and DNA. Histone variants, which are diversified by sequence or expression pattern, can profoundly alter chromatin properties. While variants in histone H2A and H3 families are well c...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2020-07-01
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| Series: | PLoS Genetics |
| Online Access: | https://doi.org/10.1371/journal.pgen.1008964 |
| _version_ | 1819141374930321408 |
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| author | Danhua Jiang Michael Borg Zdravko J Lorković Sean A Montgomery Akihisa Osakabe Ramesh Yelagandula Elin Axelsson Frédéric Berger |
| author_facet | Danhua Jiang Michael Borg Zdravko J Lorković Sean A Montgomery Akihisa Osakabe Ramesh Yelagandula Elin Axelsson Frédéric Berger |
| author_sort | Danhua Jiang |
| collection | DOAJ |
| description | Chromatin regulation of eukaryotic genomes depends on the formation of nucleosome complexes between histone proteins and DNA. Histone variants, which are diversified by sequence or expression pattern, can profoundly alter chromatin properties. While variants in histone H2A and H3 families are well characterized, the extent of diversification of histone H2B proteins is less understood. Here, we report a systematic analysis of the histone H2B family in plants, which have undergone substantial divergence during the evolution of each major group in the plant kingdom. By characterising Arabidopsis H2Bs, we substantiate this diversification and reveal potential functional specialization that parallels the phylogenetic structure of emergent clades in eudicots. In addition, we identify a new class of highly divergent H2B variants, H2B.S, that specifically accumulate during chromatin compaction of dry seed embryos in multiple species of flowering plants. Our findings thus identify unsuspected diverse properties among histone H2B proteins in plants that has manifested into potentially novel groups of histone variants. |
| first_indexed | 2024-12-22T11:53:27Z |
| format | Article |
| id | doaj.art-803ed707817a4d94a373fe359fe9d11e |
| institution | Directory Open Access Journal |
| issn | 1553-7390 1553-7404 |
| language | English |
| last_indexed | 2024-12-22T11:53:27Z |
| publishDate | 2020-07-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Genetics |
| spelling | doaj.art-803ed707817a4d94a373fe359fe9d11e2022-12-21T18:26:54ZengPublic Library of Science (PLoS)PLoS Genetics1553-73901553-74042020-07-01167e100896410.1371/journal.pgen.1008964The evolution and functional divergence of the histone H2B family in plants.Danhua JiangMichael BorgZdravko J LorkovićSean A MontgomeryAkihisa OsakabeRamesh YelagandulaElin AxelssonFrédéric BergerChromatin regulation of eukaryotic genomes depends on the formation of nucleosome complexes between histone proteins and DNA. Histone variants, which are diversified by sequence or expression pattern, can profoundly alter chromatin properties. While variants in histone H2A and H3 families are well characterized, the extent of diversification of histone H2B proteins is less understood. Here, we report a systematic analysis of the histone H2B family in plants, which have undergone substantial divergence during the evolution of each major group in the plant kingdom. By characterising Arabidopsis H2Bs, we substantiate this diversification and reveal potential functional specialization that parallels the phylogenetic structure of emergent clades in eudicots. In addition, we identify a new class of highly divergent H2B variants, H2B.S, that specifically accumulate during chromatin compaction of dry seed embryos in multiple species of flowering plants. Our findings thus identify unsuspected diverse properties among histone H2B proteins in plants that has manifested into potentially novel groups of histone variants.https://doi.org/10.1371/journal.pgen.1008964 |
| spellingShingle | Danhua Jiang Michael Borg Zdravko J Lorković Sean A Montgomery Akihisa Osakabe Ramesh Yelagandula Elin Axelsson Frédéric Berger The evolution and functional divergence of the histone H2B family in plants. PLoS Genetics |
| title | The evolution and functional divergence of the histone H2B family in plants. |
| title_full | The evolution and functional divergence of the histone H2B family in plants. |
| title_fullStr | The evolution and functional divergence of the histone H2B family in plants. |
| title_full_unstemmed | The evolution and functional divergence of the histone H2B family in plants. |
| title_short | The evolution and functional divergence of the histone H2B family in plants. |
| title_sort | evolution and functional divergence of the histone h2b family in plants |
| url | https://doi.org/10.1371/journal.pgen.1008964 |
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