Effects of Spray-Drying and Choice of Solid Carriers on Concentrations of Labrasol® and Transcutol® in Solid Self-Microemulsifying Drug Delivery Systems (SMEDDS)

Effects of Spray-Drying and Choice of Solid Carriers on Concentrations of Labrasol® and Transcutol® in Solid Self-Microemulsifying Drug Delivery Systems (SMEDDS)

Solid self-microemulsifying drug delivery systems (SMEDDS) have been used increasingly for improving the bioavailability of hydrophobic drugs. Labrasol® and Transcutol® are used widely as surfactant and solubilizer in the formulation of solid SMEDDS. We investigated the eff...

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Bibliographic Details
Main Authors: Christopher Wai-Kei Lam, Tao Yi, Liang Li
Format: Article
Language:English
Published: MDPI AG 2013-01-01
Series:Molecules
Subjects:
solid SMEDDS
spray-drying
solid carriers
excipients
LC/GC-MS
Online Access:http://www.mdpi.com/1420-3049/18/1/545

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