Radiation-induced gliosarcoma post-treatment for a recurrent pituitary adenoma: A case report
Gliosarcoma is a subtype of glioblastoma containing both gliomatous and sarcomatous components. It constitutes 2–8% of all glioblastoma. It usually affects adults in the 40–60 age group, with a higher incidence among males. Gliosarcoma may arise de-novo or be secondarily induced post-irradiation, th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-12-01
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| Series: | Interdisciplinary Neurosurgery |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214751923001226 |
| _version_ | 1827854817039482880 |
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| author | Venkata Shashank Davuluri Balasubramanian Archana M. Yathwin Kanagavel Lawrence D'Cruze |
| author_facet | Venkata Shashank Davuluri Balasubramanian Archana M. Yathwin Kanagavel Lawrence D'Cruze |
| author_sort | Venkata Shashank Davuluri |
| collection | DOAJ |
| description | Gliosarcoma is a subtype of glioblastoma containing both gliomatous and sarcomatous components. It constitutes 2–8% of all glioblastoma. It usually affects adults in the 40–60 age group, with a higher incidence among males. Gliosarcoma may arise de-novo or be secondarily induced post-irradiation, the latter being termed secondary gliosarcoma. Radiation-induced sarcoma (RIS) is a rare entity and has an incidence of 0.03–0.3% as a late complication of irradiation. We present an infrequent case of a 55-year-old female who underwent multiple surgeries for recurrent pituitary adenoma followed by post-operative radiation. The patient presented with a recurrence of the adenoma along with a new lesion in the adjacent left temporal region that was suggestive of RIS. |
| first_indexed | 2024-03-12T11:36:30Z |
| format | Article |
| id | doaj.art-8041cf34dddd4d9299518d2fb1a455d7 |
| institution | Directory Open Access Journal |
| issn | 2214-7519 |
| language | English |
| last_indexed | 2024-03-12T11:36:30Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Interdisciplinary Neurosurgery |
| spelling | doaj.art-8041cf34dddd4d9299518d2fb1a455d72023-09-01T05:02:14ZengElsevierInterdisciplinary Neurosurgery2214-75192023-12-0134101839Radiation-induced gliosarcoma post-treatment for a recurrent pituitary adenoma: A case reportVenkata Shashank Davuluri0Balasubramanian Archana1M. Yathwin Kanagavel2Lawrence D'Cruze3Department of Neurosurgery, Sri Ramachandra Medical College (SRMC), Ramachandra Nagar, Porur, Chennai 600 116, IndiaDepartment of Pathology, Sri Ramachandra Medical College (SRMC), Ramachandra Nagar, Porur, Chennai 600 116, India; Corresponding author at: Department of Pathology, Sri Ramachandra Medical College (SRMC), Porur, Chennai 600 116, Tamil Nadu, India.MBBS student, Sri Ramachandra Medical College (SRMC), Ramachandra Nagar, Porur, Chennai 600 116, IndiaDepartment of Pathology, Sri Ramachandra Medical College (SRMC), Ramachandra Nagar, Porur, Chennai 600 116, IndiaGliosarcoma is a subtype of glioblastoma containing both gliomatous and sarcomatous components. It constitutes 2–8% of all glioblastoma. It usually affects adults in the 40–60 age group, with a higher incidence among males. Gliosarcoma may arise de-novo or be secondarily induced post-irradiation, the latter being termed secondary gliosarcoma. Radiation-induced sarcoma (RIS) is a rare entity and has an incidence of 0.03–0.3% as a late complication of irradiation. We present an infrequent case of a 55-year-old female who underwent multiple surgeries for recurrent pituitary adenoma followed by post-operative radiation. The patient presented with a recurrence of the adenoma along with a new lesion in the adjacent left temporal region that was suggestive of RIS.http://www.sciencedirect.com/science/article/pii/S2214751923001226GliosarcomaRadiation-inducedRecurrentPituitary adenoma |
| spellingShingle | Venkata Shashank Davuluri Balasubramanian Archana M. Yathwin Kanagavel Lawrence D'Cruze Radiation-induced gliosarcoma post-treatment for a recurrent pituitary adenoma: A case report Interdisciplinary Neurosurgery Gliosarcoma Radiation-induced Recurrent Pituitary adenoma |
| title | Radiation-induced gliosarcoma post-treatment for a recurrent pituitary adenoma: A case report |
| title_full | Radiation-induced gliosarcoma post-treatment for a recurrent pituitary adenoma: A case report |
| title_fullStr | Radiation-induced gliosarcoma post-treatment for a recurrent pituitary adenoma: A case report |
| title_full_unstemmed | Radiation-induced gliosarcoma post-treatment for a recurrent pituitary adenoma: A case report |
| title_short | Radiation-induced gliosarcoma post-treatment for a recurrent pituitary adenoma: A case report |
| title_sort | radiation induced gliosarcoma post treatment for a recurrent pituitary adenoma a case report |
| topic | Gliosarcoma Radiation-induced Recurrent Pituitary adenoma |
| url | http://www.sciencedirect.com/science/article/pii/S2214751923001226 |
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