Profiling the polyadenylated transcriptome of extracellular vesicles with long-read nanopore sequencing

Profiling the polyadenylated transcriptome of extracellular vesicles with long-read nanopore sequencing

Abstract Background While numerous studies have described the transcriptomes of extracellular vesicles (EVs) in different cellular contexts, these efforts have typically relied on sequencing methods requiring RNA fragmentation, which limits interpretations on the integrity and isoform diversity of E...

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Bibliographic Details
Main Authors: Juan-Carlos A. Padilla, Seda Barutcu, Ludovic Malet, Gabrielle Deschamps-Francoeur, Virginie Calderon, Eunjeong Kwon, Eric Lécuyer
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Genomics
Subjects:
Extracellular vesicles
Long-Read RNA Sequencing
Nanopore sequencing
Polyadenylated transcriptome
Poly-A
mRNA
Online Access:https://doi.org/10.1186/s12864-023-09552-6

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