BRCA Mutations Increase Fertility in Families at Hereditary Breast/Ovarian Cancer Risk.

BRCA Mutations Increase Fertility in Families at Hereditary Breast/Ovarian Cancer Risk.

Deleterious mutations in the BRCA genes are responsible for a small, but significant, proportion of breast and ovarian cancers (5 - 10 %). Proof of de novo mutations in hereditary breast/ovarian cancer (HBOC) families is rare, in contrast to founder mutations, thousands of years old, that may be car...

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Bibliographic Details
Main Authors:	Fabrice Kwiatkowski, Marie Arbre, Yannick Bidet, Claire Laquet, Nancy Uhrhammer, Yves-Jean Bignon
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4457526?pdf=render

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