The effect of chloroquine phosphate on C-reactive protein and erythrocyte sedimentation rate measurement in knee osteoarthritic patients.

Osteoarthritis (OA) is the most common articular disease world wide. It is the result of both mechanical and biological events that destabilize the normal coupling of degeneration synthesis of articular cartilage and subchondral bone. Rheumatologist often routinely order tests for rheumatoid factor...

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Main Author: Eman S. S.
Format: Article
Language:English
Published: College of Pharmacy / Mustansiriyah University 2011-12-01
Series:Al-Mustansiriyah Journal of Pharmaceutical Sciences
Online Access:https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/291
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author Eman S. S.
author_facet Eman S. S.
author_sort Eman S. S.
collection DOAJ
description Osteoarthritis (OA) is the most common articular disease world wide. It is the result of both mechanical and biological events that destabilize the normal coupling of degeneration synthesis of articular cartilage and subchondral bone. Rheumatologist often routinely order tests for rheumatoid factor and erythrocyte sedimentation rate (ESR) for all patients with joint complaints as well as C - reactive protein (CRP) as a laboratory marker important in the assessment of inflammation. Anti malarial drugs are used for treatment of many rheumatic diseases. Chloroquine phosphate (CQP) was used previously as a disease modifying anti rheumatic drug and in this study its effect appears through decreasing the measurement of erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) in knee osteoarthritic patients (KOA). Abbreviation: HCQ, hydroxy chloroquine; CQ, chloroquine; DMARD, disease modifying anti rheumatic drug; APP, acute phase protein; ACR, American College of Rheumatology; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus; RF, rheumatoid factor.
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spelling doaj.art-8044b681afb144fb99b1dabb4e3d43a62024-04-04T06:58:57ZengCollege of Pharmacy / Mustansiriyah UniversityAl-Mustansiriyah Journal of Pharmaceutical Sciences1815-09932959-183X2011-12-0110210.32947/ajps.v10i2.291The effect of chloroquine phosphate on C-reactive protein and erythrocyte sedimentation rate measurement in knee osteoarthritic patients.Eman S. S.0College of Pharmacy University of Baghdad. Osteoarthritis (OA) is the most common articular disease world wide. It is the result of both mechanical and biological events that destabilize the normal coupling of degeneration synthesis of articular cartilage and subchondral bone. Rheumatologist often routinely order tests for rheumatoid factor and erythrocyte sedimentation rate (ESR) for all patients with joint complaints as well as C - reactive protein (CRP) as a laboratory marker important in the assessment of inflammation. Anti malarial drugs are used for treatment of many rheumatic diseases. Chloroquine phosphate (CQP) was used previously as a disease modifying anti rheumatic drug and in this study its effect appears through decreasing the measurement of erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) in knee osteoarthritic patients (KOA). Abbreviation: HCQ, hydroxy chloroquine; CQ, chloroquine; DMARD, disease modifying anti rheumatic drug; APP, acute phase protein; ACR, American College of Rheumatology; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus; RF, rheumatoid factor. https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/291
spellingShingle Eman S. S.
The effect of chloroquine phosphate on C-reactive protein and erythrocyte sedimentation rate measurement in knee osteoarthritic patients.
Al-Mustansiriyah Journal of Pharmaceutical Sciences
title The effect of chloroquine phosphate on C-reactive protein and erythrocyte sedimentation rate measurement in knee osteoarthritic patients.
title_full The effect of chloroquine phosphate on C-reactive protein and erythrocyte sedimentation rate measurement in knee osteoarthritic patients.
title_fullStr The effect of chloroquine phosphate on C-reactive protein and erythrocyte sedimentation rate measurement in knee osteoarthritic patients.
title_full_unstemmed The effect of chloroquine phosphate on C-reactive protein and erythrocyte sedimentation rate measurement in knee osteoarthritic patients.
title_short The effect of chloroquine phosphate on C-reactive protein and erythrocyte sedimentation rate measurement in knee osteoarthritic patients.
title_sort effect of chloroquine phosphate on c reactive protein and erythrocyte sedimentation rate measurement in knee osteoarthritic patients
url https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/291
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AT emanss effectofchloroquinephosphateoncreactiveproteinanderythrocytesedimentationratemeasurementinkneeosteoarthriticpatients