Twelve-Year Outcomes of Pterygium Excision with Conjunctival Autograft versus Intraoperative Mitomycin C in Double-Head Pterygium Surgery
Purpose. The study aims to compare the long-term outcome of conjunctival autograft (CAU) and mitomycin C (MMC) in double-head pterygium surgery. Methods. This is a follow-up study of a comparative interventional trial. Thirty-nine eyes of the 36 patients with double-head pterygium excision in the or...
| Glavni autori: | , , , , , , |
|---|---|
| Format: | Članak |
| Jezik: | English |
| Izdano: |
Hindawi Limited
2015-01-01
|
| Serija: | Journal of Ophthalmology |
| Online pristup: | http://dx.doi.org/10.1155/2015/891582 |
| _version_ | 1827006671340175360 |
|---|---|
| author | Tommy C. Y. Chan Raymond L. M. Wong Emmy Y. M. Li Hunter K. L. Yuen Emily F. Y. Yeung Vishal Jhanji Ian Y. H. Wong |
| author_facet | Tommy C. Y. Chan Raymond L. M. Wong Emmy Y. M. Li Hunter K. L. Yuen Emily F. Y. Yeung Vishal Jhanji Ian Y. H. Wong |
| author_sort | Tommy C. Y. Chan |
| collection | DOAJ |
| description | Purpose. The study aims to compare the long-term outcome of conjunctival autograft (CAU) and mitomycin C (MMC) in double-head pterygium surgery. Methods. This is a follow-up study of a comparative interventional trial. Thirty-nine eyes of the 36 patients with double-head pterygium excision in the original study 12 years ago were recruited for clinical assessment. Seven out of the 36 patients were lost. In the original study, each eye with double-head pterygium was randomized to have pterygium excision with CAU on one “head” (temporal or nasal) and MMC on the other “head.” All patients were invited for clinical assessment for conjunctival bed status and the presence of pterygium recurrence in the current study. Results. There was no significant difference between the size, morphology, and type of pterygium among the two treatment groups. The recurrence rate of CAU group and MMC group 12 years after excision was 6.3% and 28.1%, respectively (P=0.020). Among eyes without recurrence, the conjunctival bed was graded higher in the MMC group than the CAU group (P=0.024). Conclusion. The use of conjunctival autograft has a significantly lower long-term recurrence rate than mitomycin C in double-head pterygium surgery. |
| first_indexed | 2025-02-18T12:07:44Z |
| format | Article |
| id | doaj.art-8044c61ed26a42b7abae57a4aa55b51d |
| institution | Directory Open Access Journal |
| issn | 2090-004X 2090-0058 |
| language | English |
| last_indexed | 2025-02-18T12:07:44Z |
| publishDate | 2015-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj.art-8044c61ed26a42b7abae57a4aa55b51d2024-11-02T05:08:22ZengHindawi LimitedJournal of Ophthalmology2090-004X2090-00582015-01-01201510.1155/2015/891582891582Twelve-Year Outcomes of Pterygium Excision with Conjunctival Autograft versus Intraoperative Mitomycin C in Double-Head Pterygium SurgeryTommy C. Y. Chan0Raymond L. M. Wong1Emmy Y. M. Li2Hunter K. L. Yuen3Emily F. Y. Yeung4Vishal Jhanji5Ian Y. H. Wong6Hong Kong Eye Hospital, 147K Argyle Street, Kowloon, Hong KongHong Kong Eye Hospital, 147K Argyle Street, Kowloon, Hong KongHong Kong Eye Hospital, 147K Argyle Street, Kowloon, Hong KongHong Kong Eye Hospital, 147K Argyle Street, Kowloon, Hong KongHong Kong Eye Hospital, 147K Argyle Street, Kowloon, Hong KongDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong KongDepartment of Ophthalmology, The University of Hong Kong, Hong KongPurpose. The study aims to compare the long-term outcome of conjunctival autograft (CAU) and mitomycin C (MMC) in double-head pterygium surgery. Methods. This is a follow-up study of a comparative interventional trial. Thirty-nine eyes of the 36 patients with double-head pterygium excision in the original study 12 years ago were recruited for clinical assessment. Seven out of the 36 patients were lost. In the original study, each eye with double-head pterygium was randomized to have pterygium excision with CAU on one “head” (temporal or nasal) and MMC on the other “head.” All patients were invited for clinical assessment for conjunctival bed status and the presence of pterygium recurrence in the current study. Results. There was no significant difference between the size, morphology, and type of pterygium among the two treatment groups. The recurrence rate of CAU group and MMC group 12 years after excision was 6.3% and 28.1%, respectively (P=0.020). Among eyes without recurrence, the conjunctival bed was graded higher in the MMC group than the CAU group (P=0.024). Conclusion. The use of conjunctival autograft has a significantly lower long-term recurrence rate than mitomycin C in double-head pterygium surgery.http://dx.doi.org/10.1155/2015/891582 |
| spellingShingle | Tommy C. Y. Chan Raymond L. M. Wong Emmy Y. M. Li Hunter K. L. Yuen Emily F. Y. Yeung Vishal Jhanji Ian Y. H. Wong Twelve-Year Outcomes of Pterygium Excision with Conjunctival Autograft versus Intraoperative Mitomycin C in Double-Head Pterygium Surgery Journal of Ophthalmology |
| title | Twelve-Year Outcomes of Pterygium Excision with Conjunctival Autograft versus Intraoperative Mitomycin C in Double-Head Pterygium Surgery |
| title_full | Twelve-Year Outcomes of Pterygium Excision with Conjunctival Autograft versus Intraoperative Mitomycin C in Double-Head Pterygium Surgery |
| title_fullStr | Twelve-Year Outcomes of Pterygium Excision with Conjunctival Autograft versus Intraoperative Mitomycin C in Double-Head Pterygium Surgery |
| title_full_unstemmed | Twelve-Year Outcomes of Pterygium Excision with Conjunctival Autograft versus Intraoperative Mitomycin C in Double-Head Pterygium Surgery |
| title_short | Twelve-Year Outcomes of Pterygium Excision with Conjunctival Autograft versus Intraoperative Mitomycin C in Double-Head Pterygium Surgery |
| title_sort | twelve year outcomes of pterygium excision with conjunctival autograft versus intraoperative mitomycin c in double head pterygium surgery |
| url | http://dx.doi.org/10.1155/2015/891582 |
| work_keys_str_mv | AT tommycychan twelveyearoutcomesofpterygiumexcisionwithconjunctivalautograftversusintraoperativemitomycincindoubleheadpterygiumsurgery AT raymondlmwong twelveyearoutcomesofpterygiumexcisionwithconjunctivalautograftversusintraoperativemitomycincindoubleheadpterygiumsurgery AT emmyymli twelveyearoutcomesofpterygiumexcisionwithconjunctivalautograftversusintraoperativemitomycincindoubleheadpterygiumsurgery AT hunterklyuen twelveyearoutcomesofpterygiumexcisionwithconjunctivalautograftversusintraoperativemitomycincindoubleheadpterygiumsurgery AT emilyfyyeung twelveyearoutcomesofpterygiumexcisionwithconjunctivalautograftversusintraoperativemitomycincindoubleheadpterygiumsurgery AT vishaljhanji twelveyearoutcomesofpterygiumexcisionwithconjunctivalautograftversusintraoperativemitomycincindoubleheadpterygiumsurgery AT ianyhwong twelveyearoutcomesofpterygiumexcisionwithconjunctivalautograftversusintraoperativemitomycincindoubleheadpterygiumsurgery |