Dose-Area Product Determination and Beam Monitor Calibration for the Fixed Beam of the Shanghai Advanced Proton Therapy Facility
Research conducted to-date, makes use of the IBA-Lynx scintillating screen and radiochromic film to analyze the proton field uniformity for dose-area product (DAP) determination. In this paper, the machine log file based reconstruction is proposed to calculate the field uniformity to simplify the me...
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MDPI AG
2022-04-01
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| Online Access: | https://www.mdpi.com/2076-3417/12/9/4111 |
| _version_ | 1797505831983382528 |
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| author | Libing Zhu Manzhou Zhang Xincheng Xiang Xiangang Wang |
| author_facet | Libing Zhu Manzhou Zhang Xincheng Xiang Xiangang Wang |
| author_sort | Libing Zhu |
| collection | DOAJ |
| description | Research conducted to-date, makes use of the IBA-Lynx scintillating screen and radiochromic film to analyze the proton field uniformity for dose-area product (DAP) determination. In this paper, the machine log file based reconstruction is proposed to calculate the field uniformity to simplify the measurement. In order to calculate the field uniformity, the dose distribution is reconstructed based on the machine log file with matRad (an open source software for analytical dose calculation in MATLAB). After acquisition of the dose distribution, the field flatness and symmetry are calculated automatically for different proton energies. A comprehensive comparison of DAP determined with Bragg peak chamber (BPC) and Markus chamber (MC) is presented. The actual delivered dose is reconstructed with the log file to analyze the lateral dose distribution of the scanned field. DAP of different energies are calculated ranging from 70.6 MeV to 235 MeV. The percentage difference is calculated, illustrating the DAP discrepancy between the MC and BPC to the mean value. The percentage difference ranges from −0.19% to 1.26%. The variation between DAP measured with the BPC and MC peaks at −2.5%. The log file based reconstruction to calculate field uniformity can be an alternative for DAP determination. The direct method using a large-area Bragg peak chamber is investigated. The two methods to determine DAP and calibrate beam monitor illustrate consistent results. |
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| id | doaj.art-8045c54ebbde4764b7d006f5aa95fb66 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-10T04:23:57Z |
| publishDate | 2022-04-01 |
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| spelling | doaj.art-8045c54ebbde4764b7d006f5aa95fb662023-11-23T07:44:20ZengMDPI AGApplied Sciences2076-34172022-04-01129411110.3390/app12094111Dose-Area Product Determination and Beam Monitor Calibration for the Fixed Beam of the Shanghai Advanced Proton Therapy FacilityLibing Zhu0Manzhou Zhang1Xincheng Xiang2Xiangang Wang3Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084, ChinaShanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, ChinaInstitute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084, ChinaInstitute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084, ChinaResearch conducted to-date, makes use of the IBA-Lynx scintillating screen and radiochromic film to analyze the proton field uniformity for dose-area product (DAP) determination. In this paper, the machine log file based reconstruction is proposed to calculate the field uniformity to simplify the measurement. In order to calculate the field uniformity, the dose distribution is reconstructed based on the machine log file with matRad (an open source software for analytical dose calculation in MATLAB). After acquisition of the dose distribution, the field flatness and symmetry are calculated automatically for different proton energies. A comprehensive comparison of DAP determined with Bragg peak chamber (BPC) and Markus chamber (MC) is presented. The actual delivered dose is reconstructed with the log file to analyze the lateral dose distribution of the scanned field. DAP of different energies are calculated ranging from 70.6 MeV to 235 MeV. The percentage difference is calculated, illustrating the DAP discrepancy between the MC and BPC to the mean value. The percentage difference ranges from −0.19% to 1.26%. The variation between DAP measured with the BPC and MC peaks at −2.5%. The log file based reconstruction to calculate field uniformity can be an alternative for DAP determination. The direct method using a large-area Bragg peak chamber is investigated. The two methods to determine DAP and calibrate beam monitor illustrate consistent results.https://www.mdpi.com/2076-3417/12/9/4111dose-area productreference dosimetryproton beambeam monitor calibration |
| spellingShingle | Libing Zhu Manzhou Zhang Xincheng Xiang Xiangang Wang Dose-Area Product Determination and Beam Monitor Calibration for the Fixed Beam of the Shanghai Advanced Proton Therapy Facility Applied Sciences dose-area product reference dosimetry proton beam beam monitor calibration |
| title | Dose-Area Product Determination and Beam Monitor Calibration for the Fixed Beam of the Shanghai Advanced Proton Therapy Facility |
| title_full | Dose-Area Product Determination and Beam Monitor Calibration for the Fixed Beam of the Shanghai Advanced Proton Therapy Facility |
| title_fullStr | Dose-Area Product Determination and Beam Monitor Calibration for the Fixed Beam of the Shanghai Advanced Proton Therapy Facility |
| title_full_unstemmed | Dose-Area Product Determination and Beam Monitor Calibration for the Fixed Beam of the Shanghai Advanced Proton Therapy Facility |
| title_short | Dose-Area Product Determination and Beam Monitor Calibration for the Fixed Beam of the Shanghai Advanced Proton Therapy Facility |
| title_sort | dose area product determination and beam monitor calibration for the fixed beam of the shanghai advanced proton therapy facility |
| topic | dose-area product reference dosimetry proton beam beam monitor calibration |
| url | https://www.mdpi.com/2076-3417/12/9/4111 |
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