Association between gestational visit‐to‐visit blood pressure variability and adverse neonatal outcomes
Abstract The authors aimed to explore the association between visit‐to‐visit blood pressure variability (BPV) in pregnant women and adverse neonatal outcomes. The study included 52 891 pregnant women. BPV was calculated as standard deviation (SD) and coefficient of variation (CV) of systolic blood p...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-06-01
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| Series: | The Journal of Clinical Hypertension |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/jch.14500 |
| _version_ | 1827778963106168832 |
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| author | Yingjie Gu Haofan Shi Weijian Zeng Yulong Zheng Mengnan Yang Mengru Sun Hong Shi Wei Gu |
| author_facet | Yingjie Gu Haofan Shi Weijian Zeng Yulong Zheng Mengnan Yang Mengru Sun Hong Shi Wei Gu |
| author_sort | Yingjie Gu |
| collection | DOAJ |
| description | Abstract The authors aimed to explore the association between visit‐to‐visit blood pressure variability (BPV) in pregnant women and adverse neonatal outcomes. The study included 52 891 pregnant women. BPV was calculated as standard deviation (SD) and coefficient of variation (CV) of systolic blood pressure (SBP) or diastolic blood pressure (DBP). All participants were divided into four groups by the quartiles of BPV. When comparing the highest quartiles to the lowest quartiles of DBP SD in all participants, the fully adjusted ORs were 1.19 (95% CI 1.11–1.27, p for trend < .001) for fetal distress, 1.32 (95% CI 1.14–1.54, p for trend < .001) for small for gestational age, 1.32 (95% CI 1.06–1.63, p for trend = .003) for 1‐min Apgar score ≤ 7. When comparing the highest quartiles to the lowest quartiles of DBP CV, ORs were 1.22 (95% CI 1.14–1.30, p for trend < .001) for fetal distress, 1.38 (95% CI 1.17–1.61, p for trend < .001) for small for gestational age, 1.43 (95% CI 1.14–1.79, p for trend < .001) for 1‐min Apgar score ≤ 7. ORs for preterm birth and 5‐min Apgar score ≤ 7 were not statistically significant. However, in participants with gestational hypertension or preeclampsia, ORs for preterm birth were 2.80 (95% CI 1.99–3.94, p for trend < .001) in DBP SD and 3.25 (95% CI 2.24–4.72, p for trend < .001) in DBP CV when extreme quartiles were compared. In conclusion, higher visit‐to‐visit BPV was associated with adverse neonatal outcomes. |
| first_indexed | 2024-03-11T14:43:27Z |
| format | Article |
| id | doaj.art-804688d854094eb9b1f904ed5cfc3d25 |
| institution | Directory Open Access Journal |
| issn | 1524-6175 1751-7176 |
| language | English |
| last_indexed | 2024-03-11T14:43:27Z |
| publishDate | 2022-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Journal of Clinical Hypertension |
| spelling | doaj.art-804688d854094eb9b1f904ed5cfc3d252023-10-30T13:26:02ZengWileyThe Journal of Clinical Hypertension1524-61751751-71762022-06-0124677978810.1111/jch.14500Association between gestational visit‐to‐visit blood pressure variability and adverse neonatal outcomesYingjie Gu0Haofan Shi1Weijian Zeng2Yulong Zheng3Mengnan Yang4Mengru Sun5Hong Shi6Wei Gu7The International Peace Maternity and Child Health Hospital School of Medicine Shanghai Jiao Tong University Shanghai ChinaThe International Peace Maternity and Child Health Hospital School of Medicine Shanghai Jiao Tong University Shanghai ChinaThe International Peace Maternity and Child Health Hospital School of Medicine Shanghai Jiao Tong University Shanghai ChinaThe International Peace Maternity and Child Health Hospital School of Medicine Shanghai Jiao Tong University Shanghai ChinaThe International Peace Maternity and Child Health Hospital School of Medicine Shanghai Jiao Tong University Shanghai ChinaThe International Peace Maternity and Child Health Hospital School of Medicine Shanghai Jiao Tong University Shanghai ChinaThe International Peace Maternity and Child Health Hospital School of Medicine Shanghai Jiao Tong University Shanghai ChinaThe International Peace Maternity and Child Health Hospital School of Medicine Shanghai Jiao Tong University Shanghai ChinaAbstract The authors aimed to explore the association between visit‐to‐visit blood pressure variability (BPV) in pregnant women and adverse neonatal outcomes. The study included 52 891 pregnant women. BPV was calculated as standard deviation (SD) and coefficient of variation (CV) of systolic blood pressure (SBP) or diastolic blood pressure (DBP). All participants were divided into four groups by the quartiles of BPV. When comparing the highest quartiles to the lowest quartiles of DBP SD in all participants, the fully adjusted ORs were 1.19 (95% CI 1.11–1.27, p for trend < .001) for fetal distress, 1.32 (95% CI 1.14–1.54, p for trend < .001) for small for gestational age, 1.32 (95% CI 1.06–1.63, p for trend = .003) for 1‐min Apgar score ≤ 7. When comparing the highest quartiles to the lowest quartiles of DBP CV, ORs were 1.22 (95% CI 1.14–1.30, p for trend < .001) for fetal distress, 1.38 (95% CI 1.17–1.61, p for trend < .001) for small for gestational age, 1.43 (95% CI 1.14–1.79, p for trend < .001) for 1‐min Apgar score ≤ 7. ORs for preterm birth and 5‐min Apgar score ≤ 7 were not statistically significant. However, in participants with gestational hypertension or preeclampsia, ORs for preterm birth were 2.80 (95% CI 1.99–3.94, p for trend < .001) in DBP SD and 3.25 (95% CI 2.24–4.72, p for trend < .001) in DBP CV when extreme quartiles were compared. In conclusion, higher visit‐to‐visit BPV was associated with adverse neonatal outcomes.https://doi.org/10.1111/jch.14500blood pressure variabilityfetal distressneonatal outcomespreterm birthsmall for gestational age |
| spellingShingle | Yingjie Gu Haofan Shi Weijian Zeng Yulong Zheng Mengnan Yang Mengru Sun Hong Shi Wei Gu Association between gestational visit‐to‐visit blood pressure variability and adverse neonatal outcomes The Journal of Clinical Hypertension blood pressure variability fetal distress neonatal outcomes preterm birth small for gestational age |
| title | Association between gestational visit‐to‐visit blood pressure variability and adverse neonatal outcomes |
| title_full | Association between gestational visit‐to‐visit blood pressure variability and adverse neonatal outcomes |
| title_fullStr | Association between gestational visit‐to‐visit blood pressure variability and adverse neonatal outcomes |
| title_full_unstemmed | Association between gestational visit‐to‐visit blood pressure variability and adverse neonatal outcomes |
| title_short | Association between gestational visit‐to‐visit blood pressure variability and adverse neonatal outcomes |
| title_sort | association between gestational visit to visit blood pressure variability and adverse neonatal outcomes |
| topic | blood pressure variability fetal distress neonatal outcomes preterm birth small for gestational age |
| url | https://doi.org/10.1111/jch.14500 |
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