Neutrophils from Patients with Primary Ciliary Dyskinesia Display Reduced Chemotaxis to CXCR2 Ligands

Neutrophils from Patients with Primary Ciliary Dyskinesia Display Reduced Chemotaxis to CXCR2 Ligands

Primary ciliary dyskinesia (PCD), cystic fibrosis (CF), and chronic obstructive airway disease are characterized by neutrophilic inflammation in the lungs. In CF and chronic obstructive airway disease, improper functioning of neutrophils has been demonstrated. We hypothesized that the pulmonary dama...

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Bibliographic Details
Main Authors: Maaike Cockx, Mieke Gouwy, Véronique Godding, Kris De Boeck, Jo Van Damme, Mieke Boon, Sofie Struyf
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
chemokines
chemotaxis
cytokines
IL-1
inflammation
neutrophils
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01126/full

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