Effects of miR-214 on adenosine A2A receptor and carboxymethyl chitosan nanoparticles on the function of keloid fibroblasts and their mechanisms

Effects of miR-214 on adenosine A2A receptor and carboxymethyl chitosan nanoparticles on the function of keloid fibroblasts and their mechanisms

Abstract This work prepared and investigated the impact of carboxymethyl chitosan nanoparticles (MC-NPs) on the proliferative capability of keloid fibroblasts (KFBs) while analyzing the mechanistic roles of miR-214 and adenosine A2A receptor (A2AR) in fibroblasts within hypertrophic scars. MC-NPs we...

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Bibliographic Details
Main Authors: Yong Du, Jing Liu, Qing Hao, Shun Wang, Aijun Zhang, Yongzhong Li, Ninghan Feng
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Subjects:
miR-214
Keloid fibroblasts
Adenosine A2AR
Cell apoptosis
Cell proliferation
Carboxymethyl chitosan nanoparticles
Online Access:https://doi.org/10.1038/s41598-024-54125-6

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