The Conners Continuous Performance Test CPT3™: Is it a reliable marker to predict neurocognitive dysfunction in Myalgic encephalomyelitis/chronic fatigue syndrome?
IntroductionThe main objective is to delimit the cognitive dysfunction associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) in adult patients by applying the Continuous Performance Test (CPT3™). Additionally, provide empirical evidence on the usefulness of this computerized ne...
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Frontiers Media S.A.
2023-02-01
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| Series: | Frontiers in Psychology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyg.2023.1127193/full |
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| author | Judith Fernández-Quirós Judith Fernández-Quirós Marcos Lacasa-Cazcarra Jose Alegre-Martín Ramón Sanmartín-Sentañes Miriam Almirall Patricia Launois-Obregón Jesús Castro-Marrero Amanda Rodríguez-Urrutia Amanda Rodríguez-Urrutia Amanda Rodríguez-Urrutia Amanda Rodríguez-Urrutia Jose A. Navarro-Sanchis Jose A. Navarro-Sanchis J. Antoni Ramos-Quiroga J. Antoni Ramos-Quiroga J. Antoni Ramos-Quiroga J. Antoni Ramos-Quiroga |
| author_facet | Judith Fernández-Quirós Judith Fernández-Quirós Marcos Lacasa-Cazcarra Jose Alegre-Martín Ramón Sanmartín-Sentañes Miriam Almirall Patricia Launois-Obregón Jesús Castro-Marrero Amanda Rodríguez-Urrutia Amanda Rodríguez-Urrutia Amanda Rodríguez-Urrutia Amanda Rodríguez-Urrutia Jose A. Navarro-Sanchis Jose A. Navarro-Sanchis J. Antoni Ramos-Quiroga J. Antoni Ramos-Quiroga J. Antoni Ramos-Quiroga J. Antoni Ramos-Quiroga |
| author_sort | Judith Fernández-Quirós |
| collection | DOAJ |
| description | IntroductionThe main objective is to delimit the cognitive dysfunction associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) in adult patients by applying the Continuous Performance Test (CPT3™). Additionally, provide empirical evidence on the usefulness of this computerized neuropsychological test to assess ME/CFS.MethodThe final sample (n = 225; 158 Patients/67 Healthy controls) were recruited in a Central Sensitization Syndromes (CSS) specialized unit in a tertiary hospital. All participants were administered this neuropsychological test.ResultsThere were significant differences between ME/CFS and healthy controls in all the main measures of CPT3™. Mainly, patients had a worse indicator of inattentiveness, sustained attention, vigilance, impulsivity, slow reaction time, and more atypical T-scores, which is associated with a likelihood of having a disorder characterized by attention deficits, such as Attention Deficit Hyperactivity Disorder (ADHD). In addition, relevant correlations were obtained between the CPT3™ variables in the patient’s group. The most discriminative indicators of ME/CFS patients were Variability and Hit Reaction Time, both measures of response speed.ConclusionThe CPT3™ is a helpful tool to discriminate neurocognitive impairments from attention and response speed in ME/CFS patients, and it could be used as a marker of ME/CFS severity for diagnosing or monitoring this disease. |
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| language | English |
| last_indexed | 2024-04-10T07:07:20Z |
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| spelling | doaj.art-8055af4f244943a199e60589528272822023-02-27T06:21:30ZengFrontiers Media S.A.Frontiers in Psychology1664-10782023-02-011410.3389/fpsyg.2023.11271931127193The Conners Continuous Performance Test CPT3™: Is it a reliable marker to predict neurocognitive dysfunction in Myalgic encephalomyelitis/chronic fatigue syndrome?Judith Fernández-Quirós0Judith Fernández-Quirós1Marcos Lacasa-Cazcarra2Jose Alegre-Martín3Ramón Sanmartín-Sentañes4Miriam Almirall5Patricia Launois-Obregón6Jesús Castro-Marrero7Amanda Rodríguez-Urrutia8Amanda Rodríguez-Urrutia9Amanda Rodríguez-Urrutia10Amanda Rodríguez-Urrutia11Jose A. Navarro-Sanchis12Jose A. Navarro-Sanchis13J. Antoni Ramos-Quiroga14J. Antoni Ramos-Quiroga15J. Antoni Ramos-Quiroga16J. Antoni Ramos-Quiroga17Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Unit, Division of Rheumatology, Vall d’Hebron Hospital Research Institute Universitat Autònoma de Barcelona, Barcelona, SpainDepartment of Mental Health, Hospital Universitari Vall d’Hebron, Barcelona, Spaine-Health Center, Universitat Oberta de Catalunya, Barcelona, SpainMyalgic Encephalomyelitis/Chronic Fatigue Syndrome Unit, Division of Rheumatology, Vall d’Hebron Hospital Research Institute Universitat Autònoma de Barcelona, Barcelona, SpainMyalgic Encephalomyelitis/Chronic Fatigue Syndrome Unit, Division of Rheumatology, Vall d’Hebron Hospital Research Institute Universitat Autònoma de Barcelona, Barcelona, SpainMyalgic Encephalomyelitis/Chronic Fatigue Syndrome Unit, Division of Rheumatology, Vall d’Hebron Hospital Research Institute Universitat Autònoma de Barcelona, Barcelona, SpainMyalgic Encephalomyelitis/Chronic Fatigue Syndrome Unit, Division of Rheumatology, Vall d’Hebron Hospital Research Institute Universitat Autònoma de Barcelona, Barcelona, SpainMyalgic Encephalomyelitis/Chronic Fatigue Syndrome Unit, Division of Rheumatology, Vall d’Hebron Hospital Research Institute Universitat Autònoma de Barcelona, Barcelona, SpainDepartment of Mental Health, Hospital Universitari Vall d’Hebron, Barcelona, SpainGroup of Psychiatry, Mental Health and Addictions, Vall d’Hebron Research Institute (VHIR), Barcelona, SpainBiomedical Network Research Centre on Mental Health (CIBERSAM), Barcelona, SpainDepartment of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona, Barcelona, SpainDepartment of Mental Health, Hospital Universitari Vall d’Hebron, Barcelona, SpainGroup of Psychiatry, Mental Health and Addictions, Vall d’Hebron Research Institute (VHIR), Barcelona, SpainDepartment of Mental Health, Hospital Universitari Vall d’Hebron, Barcelona, SpainGroup of Psychiatry, Mental Health and Addictions, Vall d’Hebron Research Institute (VHIR), Barcelona, SpainBiomedical Network Research Centre on Mental Health (CIBERSAM), Barcelona, SpainDepartment of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona, Barcelona, SpainIntroductionThe main objective is to delimit the cognitive dysfunction associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) in adult patients by applying the Continuous Performance Test (CPT3™). Additionally, provide empirical evidence on the usefulness of this computerized neuropsychological test to assess ME/CFS.MethodThe final sample (n = 225; 158 Patients/67 Healthy controls) were recruited in a Central Sensitization Syndromes (CSS) specialized unit in a tertiary hospital. All participants were administered this neuropsychological test.ResultsThere were significant differences between ME/CFS and healthy controls in all the main measures of CPT3™. Mainly, patients had a worse indicator of inattentiveness, sustained attention, vigilance, impulsivity, slow reaction time, and more atypical T-scores, which is associated with a likelihood of having a disorder characterized by attention deficits, such as Attention Deficit Hyperactivity Disorder (ADHD). In addition, relevant correlations were obtained between the CPT3™ variables in the patient’s group. The most discriminative indicators of ME/CFS patients were Variability and Hit Reaction Time, both measures of response speed.ConclusionThe CPT3™ is a helpful tool to discriminate neurocognitive impairments from attention and response speed in ME/CFS patients, and it could be used as a marker of ME/CFS severity for diagnosing or monitoring this disease.https://www.frontiersin.org/articles/10.3389/fpsyg.2023.1127193/fullneuropsychological testcognitive impairmentscontinuous performance testCPT3™neurocognitive dysfunctionCentral Sensitization Syndromes |
| spellingShingle | Judith Fernández-Quirós Judith Fernández-Quirós Marcos Lacasa-Cazcarra Jose Alegre-Martín Ramón Sanmartín-Sentañes Miriam Almirall Patricia Launois-Obregón Jesús Castro-Marrero Amanda Rodríguez-Urrutia Amanda Rodríguez-Urrutia Amanda Rodríguez-Urrutia Amanda Rodríguez-Urrutia Jose A. Navarro-Sanchis Jose A. Navarro-Sanchis J. Antoni Ramos-Quiroga J. Antoni Ramos-Quiroga J. Antoni Ramos-Quiroga J. Antoni Ramos-Quiroga The Conners Continuous Performance Test CPT3™: Is it a reliable marker to predict neurocognitive dysfunction in Myalgic encephalomyelitis/chronic fatigue syndrome? Frontiers in Psychology neuropsychological test cognitive impairments continuous performance test CPT3™ neurocognitive dysfunction Central Sensitization Syndromes |
| title | The Conners Continuous Performance Test CPT3™: Is it a reliable marker to predict neurocognitive dysfunction in Myalgic encephalomyelitis/chronic fatigue syndrome? |
| title_full | The Conners Continuous Performance Test CPT3™: Is it a reliable marker to predict neurocognitive dysfunction in Myalgic encephalomyelitis/chronic fatigue syndrome? |
| title_fullStr | The Conners Continuous Performance Test CPT3™: Is it a reliable marker to predict neurocognitive dysfunction in Myalgic encephalomyelitis/chronic fatigue syndrome? |
| title_full_unstemmed | The Conners Continuous Performance Test CPT3™: Is it a reliable marker to predict neurocognitive dysfunction in Myalgic encephalomyelitis/chronic fatigue syndrome? |
| title_short | The Conners Continuous Performance Test CPT3™: Is it a reliable marker to predict neurocognitive dysfunction in Myalgic encephalomyelitis/chronic fatigue syndrome? |
| title_sort | conners continuous performance test cpt3™ is it a reliable marker to predict neurocognitive dysfunction in myalgic encephalomyelitis chronic fatigue syndrome |
| topic | neuropsychological test cognitive impairments continuous performance test CPT3™ neurocognitive dysfunction Central Sensitization Syndromes |
| url | https://www.frontiersin.org/articles/10.3389/fpsyg.2023.1127193/full |
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