Exhaled Breath Condensate in Childhood Asthma: A Review and Current Perspective
Exhaled breath condensate (EBC) was introduced more than two decades ago as a novel, non-invasive tool to assess airway inflammation. This review summarizes the latest literature on the various markers in EBC to predict asthma in children. Despite many recommendations and two comprehensive Task Forc...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-04-01
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| Series: | Frontiers in Pediatrics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fped.2019.00150/full |
| _version_ | 1811270187820777472 |
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| author | Michiel A. G. E. Bannier Philippe P. R. Rosias Quirijn Jöbsis Edward Dompeling |
| author_facet | Michiel A. G. E. Bannier Philippe P. R. Rosias Quirijn Jöbsis Edward Dompeling |
| author_sort | Michiel A. G. E. Bannier |
| collection | DOAJ |
| description | Exhaled breath condensate (EBC) was introduced more than two decades ago as a novel, non-invasive tool to assess airway inflammation. This review summarizes the latest literature on the various markers in EBC to predict asthma in children. Despite many recommendations and two comprehensive Task Force reports, there is still large heterogeneity in published data. The biggest issue remains a lack of standardization regarding EBC collection, preservation, processing, and analysis. As a result, published studies show mixed or conflicting results, questioning the reproducibility of findings. A joint, multicenter research study is urgently needed to address the necessary methodological standardization. |
| first_indexed | 2024-04-12T21:56:22Z |
| format | Article |
| id | doaj.art-805643f63fab4287b1b7b7661d84c99d |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-04-12T21:56:22Z |
| publishDate | 2019-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-805643f63fab4287b1b7b7661d84c99d2022-12-22T03:15:18ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602019-04-01710.3389/fped.2019.00150455006Exhaled Breath Condensate in Childhood Asthma: A Review and Current PerspectiveMichiel A. G. E. Bannier0Philippe P. R. Rosias1Quirijn Jöbsis2Edward Dompeling3Department of Pediatric Respiratory Medicine, School for Public Health and Primary Care (CAPHRI), Maastricht University Medical Center, Maastricht, NetherlandsDepartment of Pediatrics, Zuyderland Medical Center, Sittard, NetherlandsDepartment of Pediatric Respiratory Medicine, School for Public Health and Primary Care (CAPHRI), Maastricht University Medical Center, Maastricht, NetherlandsDepartment of Pediatric Respiratory Medicine, School for Public Health and Primary Care (CAPHRI), Maastricht University Medical Center, Maastricht, NetherlandsExhaled breath condensate (EBC) was introduced more than two decades ago as a novel, non-invasive tool to assess airway inflammation. This review summarizes the latest literature on the various markers in EBC to predict asthma in children. Despite many recommendations and two comprehensive Task Force reports, there is still large heterogeneity in published data. The biggest issue remains a lack of standardization regarding EBC collection, preservation, processing, and analysis. As a result, published studies show mixed or conflicting results, questioning the reproducibility of findings. A joint, multicenter research study is urgently needed to address the necessary methodological standardization.https://www.frontiersin.org/article/10.3389/fped.2019.00150/fullasthmawheezeexhaled breath condensateexhaled breathchildren |
| spellingShingle | Michiel A. G. E. Bannier Philippe P. R. Rosias Quirijn Jöbsis Edward Dompeling Exhaled Breath Condensate in Childhood Asthma: A Review and Current Perspective Frontiers in Pediatrics asthma wheeze exhaled breath condensate exhaled breath children |
| title | Exhaled Breath Condensate in Childhood Asthma: A Review and Current Perspective |
| title_full | Exhaled Breath Condensate in Childhood Asthma: A Review and Current Perspective |
| title_fullStr | Exhaled Breath Condensate in Childhood Asthma: A Review and Current Perspective |
| title_full_unstemmed | Exhaled Breath Condensate in Childhood Asthma: A Review and Current Perspective |
| title_short | Exhaled Breath Condensate in Childhood Asthma: A Review and Current Perspective |
| title_sort | exhaled breath condensate in childhood asthma a review and current perspective |
| topic | asthma wheeze exhaled breath condensate exhaled breath children |
| url | https://www.frontiersin.org/article/10.3389/fped.2019.00150/full |
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