Vitamin D deficiency is a public health emergency among Indonesian children and adolescents: a systematic review and meta-analysis of prevalence
Purpose This study aimed to describe the prevalence of vitamin D deficiency in Indonesian children and adolescents. Methods This was a meta-analysis of prevalence using the Hartung-Knapp-Sidik-Jonkman method with a random effects model. A prediction interval was used to estimate true effects. We sea...
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| Format: | Article |
| Language: | English |
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Korean Society of Pediatric Endocrinology
2023-02-01
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| Series: | Annals of Pediatric Endocrinology & Metabolism |
| Subjects: | |
| Online Access: | http://e-apem.org/upload/pdf/apem-2244170-085.pdf |
| _version_ | 1827973041481580544 |
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| author | Gilbert Sterling Octavius Ayesha Shakila Mariska Meliani Anita Halim |
| author_facet | Gilbert Sterling Octavius Ayesha Shakila Mariska Meliani Anita Halim |
| author_sort | Gilbert Sterling Octavius |
| collection | DOAJ |
| description | Purpose This study aimed to describe the prevalence of vitamin D deficiency in Indonesian children and adolescents. Methods This was a meta-analysis of prevalence using the Hartung-Knapp-Sidik-Jonkman method with a random effects model. A prediction interval was used to estimate true effects. We searched PubMed, MEDLINE, Cochrane Library, Science Direct, Google Scholar, and 3 Indonesian databases (Indonesian Scientific Journal Database, Neliti, and Indonesia One Search). We included cross-sectional or case-control studies that provided data on the prevalence of vitamin D deficiency. We excluded case reports, case series, cohort studies, or studies outside Indonesia. We computed point prevalence by dividing the number of children with hypovitaminosis D by the total number of subjects in that study. This review was registered with PROSPERO (International Prospective Register of Systematic Reviews) (CRD42022329814). Results Of 1,397 manuscripts identified, 7 were included in this review. A total of 5,870 children were included in this meta-analysis, ranging in age from 6 months to 19 years. The prevalence of hypovitaminosis D in Indonesia was calculated as 33% (95% confidence interval [CI], 9–56) and was higher in females (60% [95% CI, 58–62]) than in males (40% [95% CI, 38–42]). Mean serum vitamin D level was 22.74 ng/mL (95% CI, 16.95–30.51) with a prediction interval of 15.96 ng/mL to 29.52 ng/mL. Conclusions Vitamin D deficiency is a public health emergency in Indonesia. Strategies to detect and treat vitamin D deficiency in Indonesian children and adolescents should be implemented immediately. |
| first_indexed | 2024-04-09T19:30:04Z |
| format | Article |
| id | doaj.art-8065ceea865f400fa3877ca969af5dfc |
| institution | Directory Open Access Journal |
| issn | 2287-1012 2287-1292 |
| language | English |
| last_indexed | 2024-04-09T19:30:04Z |
| publishDate | 2023-02-01 |
| publisher | Korean Society of Pediatric Endocrinology |
| record_format | Article |
| series | Annals of Pediatric Endocrinology & Metabolism |
| spelling | doaj.art-8065ceea865f400fa3877ca969af5dfc2023-04-05T00:54:29ZengKorean Society of Pediatric EndocrinologyAnnals of Pediatric Endocrinology & Metabolism2287-10122287-12922023-02-01281101910.6065/apem.2244170.085977Vitamin D deficiency is a public health emergency among Indonesian children and adolescents: a systematic review and meta-analysis of prevalenceGilbert Sterling OctaviusAyesha Shakila0Mariska Meliani1Anita Halim2 Department of Pediatrics, Universitas Pelita Harapan, Jakarta, Indonesia Department of Pediatrics, Universitas Pelita Harapan, Jakarta, Indonesia Department of Pediatrics, Universitas Pelita Harapan, Jakarta, IndonesiaPurpose This study aimed to describe the prevalence of vitamin D deficiency in Indonesian children and adolescents. Methods This was a meta-analysis of prevalence using the Hartung-Knapp-Sidik-Jonkman method with a random effects model. A prediction interval was used to estimate true effects. We searched PubMed, MEDLINE, Cochrane Library, Science Direct, Google Scholar, and 3 Indonesian databases (Indonesian Scientific Journal Database, Neliti, and Indonesia One Search). We included cross-sectional or case-control studies that provided data on the prevalence of vitamin D deficiency. We excluded case reports, case series, cohort studies, or studies outside Indonesia. We computed point prevalence by dividing the number of children with hypovitaminosis D by the total number of subjects in that study. This review was registered with PROSPERO (International Prospective Register of Systematic Reviews) (CRD42022329814). Results Of 1,397 manuscripts identified, 7 were included in this review. A total of 5,870 children were included in this meta-analysis, ranging in age from 6 months to 19 years. The prevalence of hypovitaminosis D in Indonesia was calculated as 33% (95% confidence interval [CI], 9–56) and was higher in females (60% [95% CI, 58–62]) than in males (40% [95% CI, 38–42]). Mean serum vitamin D level was 22.74 ng/mL (95% CI, 16.95–30.51) with a prediction interval of 15.96 ng/mL to 29.52 ng/mL. Conclusions Vitamin D deficiency is a public health emergency in Indonesia. Strategies to detect and treat vitamin D deficiency in Indonesian children and adolescents should be implemented immediately.http://e-apem.org/upload/pdf/apem-2244170-085.pdfhypovitaminosis dindonesiavitamin d deficiencypublic health emergencyprevalence |
| spellingShingle | Gilbert Sterling Octavius Ayesha Shakila Mariska Meliani Anita Halim Vitamin D deficiency is a public health emergency among Indonesian children and adolescents: a systematic review and meta-analysis of prevalence Annals of Pediatric Endocrinology & Metabolism hypovitaminosis d indonesia vitamin d deficiency public health emergency prevalence |
| title | Vitamin D deficiency is a public health emergency among Indonesian children and adolescents: a systematic review and meta-analysis of prevalence |
| title_full | Vitamin D deficiency is a public health emergency among Indonesian children and adolescents: a systematic review and meta-analysis of prevalence |
| title_fullStr | Vitamin D deficiency is a public health emergency among Indonesian children and adolescents: a systematic review and meta-analysis of prevalence |
| title_full_unstemmed | Vitamin D deficiency is a public health emergency among Indonesian children and adolescents: a systematic review and meta-analysis of prevalence |
| title_short | Vitamin D deficiency is a public health emergency among Indonesian children and adolescents: a systematic review and meta-analysis of prevalence |
| title_sort | vitamin d deficiency is a public health emergency among indonesian children and adolescents a systematic review and meta analysis of prevalence |
| topic | hypovitaminosis d indonesia vitamin d deficiency public health emergency prevalence |
| url | http://e-apem.org/upload/pdf/apem-2244170-085.pdf |
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