Correlation of Solubility Thermodynamics of Glibenclamide with Recrystallization and In Vitro Release Profile

The solubility of glibenclamide was evaluated in DMSO, NMP, 1,4-dioxane, PEG 400, Transcutol<sup>®</sup> HP, water, and aqueous mixtures (<i>T</i> = 293.15~323.15 K). It was then recrystallized to solvate and compressed into tablets, of which 30-day stability and dissolution...

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Détails bibliographiques
Auteurs principaux: Ravi Maharjan, Junoh Jeong, Ripesh Bhujel, Min-Soo Kim, Hyo-Kyung Han, Nam Ah Kim, Seong Hoon Jeong
Format: Article
Langue:English
Publié: MDPI AG 2022-02-01
Collection:Molecules
Sujets:
Accès en ligne:https://www.mdpi.com/1420-3049/27/4/1392