Dentists’ Role in Diagnosis and Management of Oral Involvement of Nasopharyngeal Carcinoma: Serial Case Report

<p>Nasopharyngeal carcinoma (NPC) is still a significant health problem due to its relatively high incidence. Rarely, NPC could extend and involve the oral cavity, and may present as an ulceration or exophytic mass.<strong> Objectives: </strong>To discuss the rare clinical appearan...

Full description

Bibliographic Details
Main Authors: Theodorus Hedwin Kadrianto, Harum Sasanti Noegroho
Format: Article
Language:English
Published: Faculty of Dentistry, Universitas Indonesia 2015-07-01
Series:Journal of Dentistry Indonesia
Subjects:
Online Access:http://jdentistry.ui.ac.id/index.php/JDI/article/view/493
_version_ 1818475446291922944
author Theodorus Hedwin Kadrianto
Harum Sasanti Noegroho
author_facet Theodorus Hedwin Kadrianto
Harum Sasanti Noegroho
author_sort Theodorus Hedwin Kadrianto
collection DOAJ
description <p>Nasopharyngeal carcinoma (NPC) is still a significant health problem due to its relatively high incidence. Rarely, NPC could extend and involve the oral cavity, and may present as an ulceration or exophytic mass.<strong> Objectives: </strong>To discuss the rare clinical appearance of NPC involving the oral cavity and the significant role of dentists in its diagnosis and management. <strong>Case Report: </strong>We reported 3 cases of NPC with oral cavity involvement. In the first two cases, the patients presented with persistent oral ulceration with bone exposure and perforation to the above structure. The third patient presented with an ulcerated exophytic mass with temporomandibular disorder. The ulceration occurred due to bone destruction by the expansion of NPC mass, which indicated advance stage of the disease. All patients were managed with twice a day 0.2% chlorhexidine gluconate rinsing in combination with placing a chlorhexidine-moistened gauze to inhibit bacterial overgrowth and prevent secondary infection. The use of chlorhexidine was substituted by saline solution during patients’ radiotherapy and chemotherapy cycles. <strong>Conclusion:</strong> Dentist’s awareness to recognize the oral cavity involvement of NPC as well as recognizing the symptoms of NPC is very important, in order to make appropriate diagnosis and oral management. The oral management will eventually affect treatment outcome and quality of life.</p><p>DOI: <span>10.14693/jdi.v22i1.493</span></p>
first_indexed 2024-12-10T09:12:41Z
format Article
id doaj.art-806b8b0a97144cd2b91497ecec5a94ff
institution Directory Open Access Journal
issn 1693-9697
2355-4800
language English
last_indexed 2024-12-10T09:12:41Z
publishDate 2015-07-01
publisher Faculty of Dentistry, Universitas Indonesia
record_format Article
series Journal of Dentistry Indonesia
spelling doaj.art-806b8b0a97144cd2b91497ecec5a94ff2022-12-22T01:54:57ZengFaculty of Dentistry, Universitas IndonesiaJournal of Dentistry Indonesia1693-96972355-48002015-07-01221293610.14693/jdi.v22i1.493391Dentists’ Role in Diagnosis and Management of Oral Involvement of Nasopharyngeal Carcinoma: Serial Case ReportTheodorus Hedwin Kadrianto0Harum Sasanti Noegroho1Oral Medicine Residency Program, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430Department of Oral Medicine, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430<p>Nasopharyngeal carcinoma (NPC) is still a significant health problem due to its relatively high incidence. Rarely, NPC could extend and involve the oral cavity, and may present as an ulceration or exophytic mass.<strong> Objectives: </strong>To discuss the rare clinical appearance of NPC involving the oral cavity and the significant role of dentists in its diagnosis and management. <strong>Case Report: </strong>We reported 3 cases of NPC with oral cavity involvement. In the first two cases, the patients presented with persistent oral ulceration with bone exposure and perforation to the above structure. The third patient presented with an ulcerated exophytic mass with temporomandibular disorder. The ulceration occurred due to bone destruction by the expansion of NPC mass, which indicated advance stage of the disease. All patients were managed with twice a day 0.2% chlorhexidine gluconate rinsing in combination with placing a chlorhexidine-moistened gauze to inhibit bacterial overgrowth and prevent secondary infection. The use of chlorhexidine was substituted by saline solution during patients’ radiotherapy and chemotherapy cycles. <strong>Conclusion:</strong> Dentist’s awareness to recognize the oral cavity involvement of NPC as well as recognizing the symptoms of NPC is very important, in order to make appropriate diagnosis and oral management. The oral management will eventually affect treatment outcome and quality of life.</p><p>DOI: <span>10.14693/jdi.v22i1.493</span></p>http://jdentistry.ui.ac.id/index.php/JDI/article/view/493exophytic massnasopharyngeal carcinomaoral involvementulceration
spellingShingle Theodorus Hedwin Kadrianto
Harum Sasanti Noegroho
Dentists’ Role in Diagnosis and Management of Oral Involvement of Nasopharyngeal Carcinoma: Serial Case Report
Journal of Dentistry Indonesia
exophytic mass
nasopharyngeal carcinoma
oral involvement
ulceration
title Dentists’ Role in Diagnosis and Management of Oral Involvement of Nasopharyngeal Carcinoma: Serial Case Report
title_full Dentists’ Role in Diagnosis and Management of Oral Involvement of Nasopharyngeal Carcinoma: Serial Case Report
title_fullStr Dentists’ Role in Diagnosis and Management of Oral Involvement of Nasopharyngeal Carcinoma: Serial Case Report
title_full_unstemmed Dentists’ Role in Diagnosis and Management of Oral Involvement of Nasopharyngeal Carcinoma: Serial Case Report
title_short Dentists’ Role in Diagnosis and Management of Oral Involvement of Nasopharyngeal Carcinoma: Serial Case Report
title_sort dentists role in diagnosis and management of oral involvement of nasopharyngeal carcinoma serial case report
topic exophytic mass
nasopharyngeal carcinoma
oral involvement
ulceration
url http://jdentistry.ui.ac.id/index.php/JDI/article/view/493
work_keys_str_mv AT theodorushedwinkadrianto dentistsroleindiagnosisandmanagementoforalinvolvementofnasopharyngealcarcinomaserialcasereport
AT harumsasantinoegroho dentistsroleindiagnosisandmanagementoforalinvolvementofnasopharyngealcarcinomaserialcasereport