Phlorizin ameliorates myocardial fibrosis by inhibiting pyroptosis through restraining HK1-mediated NLRP3 inflammasome activation

Phlorizin ameliorates myocardial fibrosis by inhibiting pyroptosis through restraining HK1-mediated NLRP3 inflammasome activation

The specific role of phlorizin (PHL), which has antioxidant, anti-inflammatory, hypoglycemic, antiarrhythmic and antiaging effects, on myocardial fibrosis (MF) and the related pharmacological mechanisms remain unknown. The objective of this study was to determine the protective actions of PHL on iso...

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Bibliographic Details
Main Authors:	Yuling Zhang, Xizhen Cheng, Yanan Wang, Haochuan Guo, Yongxing Song, Hongfang Wang, Donglai Ma
Format:	Article
Language:	English
Published:	Elsevier 2023-11-01
Series:	Heliyon
Subjects:	Myocardial fibrosis Phlorizin Pyroptosis HK1/NLRP3 signaling pathway
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844023084256

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