The role of Spike protein in infection and disease severity
Enveloped viruses especially Coronaviruses, Influenza viruses, and Human Immunodeficiency viruses pose a great risk to the human and animal populations. These viruses cause diseases of clinical and socio-economic importance with the help of their spike protein. Coronaviruses affect the respiratory,...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Verduci Editore
2022-06-01
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| Series: | Infectious Diseases and Tropical Medicine |
| Subjects: | |
| Online Access: | https://www.infectiousjournal.com/wp-content/uploads/sites/6/2022/10/e874.pdf |
| _version_ | 1797956960041041920 |
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| author | R. Adesola I. Idris |
| author_facet | R. Adesola I. Idris |
| author_sort | R. Adesola |
| collection | DOAJ |
| description | Enveloped viruses especially Coronaviruses, Influenza viruses, and Human Immunodeficiency viruses pose a great risk to the human and animal populations. These viruses cause diseases of clinical and socio-economic importance with the help of their spike protein. Coronaviruses affect the respiratory, gastrointestinal tract, and nervous system and the influenza virus affects the respiratory system while the Human Immunodeficiency Virus affects multiple systems as it invades and destroys immune cells. We aimed to review the role of spike protein in the four viruses and their effects on disease severity. We searched through online publication databases such as PubMed, Google Scholar, and Scopus to retrieve 150 scientific published articles using keywords like ‘Spike Protein’, ‘Viruses’, ‘Infection’, and ‘Diseases’. A total of 100 articles were used to write this article. Spike protein is an essential structure in viruses that causes infections and diseases in humans and animals. Targeting this protein in the development of antiviral drugs and vaccines should be a major concern. |
| first_indexed | 2024-04-10T23:57:56Z |
| format | Article |
| id | doaj.art-807551211f4f4a80953f7e359b69c34d |
| institution | Directory Open Access Journal |
| issn | 2379-4054 |
| language | English |
| last_indexed | 2024-04-10T23:57:56Z |
| publishDate | 2022-06-01 |
| publisher | Verduci Editore |
| record_format | Article |
| series | Infectious Diseases and Tropical Medicine |
| spelling | doaj.art-807551211f4f4a80953f7e359b69c34d2023-01-10T10:28:31ZengVerduci EditoreInfectious Diseases and Tropical Medicine2379-40542022-06-01810.32113/idtm_20226_874874The role of Spike protein in infection and disease severityR. Adesola0I. Idris1Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, NigeriaDepartment of Veterinary Medicine, Faculty of Veterinary Medicine, Usmanu Danfodiyo University, Sokoto, NigeriaEnveloped viruses especially Coronaviruses, Influenza viruses, and Human Immunodeficiency viruses pose a great risk to the human and animal populations. These viruses cause diseases of clinical and socio-economic importance with the help of their spike protein. Coronaviruses affect the respiratory, gastrointestinal tract, and nervous system and the influenza virus affects the respiratory system while the Human Immunodeficiency Virus affects multiple systems as it invades and destroys immune cells. We aimed to review the role of spike protein in the four viruses and their effects on disease severity. We searched through online publication databases such as PubMed, Google Scholar, and Scopus to retrieve 150 scientific published articles using keywords like ‘Spike Protein’, ‘Viruses’, ‘Infection’, and ‘Diseases’. A total of 100 articles were used to write this article. Spike protein is an essential structure in viruses that causes infections and diseases in humans and animals. Targeting this protein in the development of antiviral drugs and vaccines should be a major concern.https://www.infectiousjournal.com/wp-content/uploads/sites/6/2022/10/e874.pdfspike proteinenveloped virusescoronaviruseshivinfluenza virus |
| spellingShingle | R. Adesola I. Idris The role of Spike protein in infection and disease severity Infectious Diseases and Tropical Medicine spike protein enveloped viruses coronaviruses hiv influenza virus |
| title | The role of Spike protein in infection and disease severity |
| title_full | The role of Spike protein in infection and disease severity |
| title_fullStr | The role of Spike protein in infection and disease severity |
| title_full_unstemmed | The role of Spike protein in infection and disease severity |
| title_short | The role of Spike protein in infection and disease severity |
| title_sort | role of spike protein in infection and disease severity |
| topic | spike protein enveloped viruses coronaviruses hiv influenza virus |
| url | https://www.infectiousjournal.com/wp-content/uploads/sites/6/2022/10/e874.pdf |
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