PET/CT-guided versus CT-guided percutaneous core biopsies in the diagnosis of bone tumors and tumor-like lesions: which is the better choice?
Abstract Objective The present study aimed to evaluate the diagnostic performance and safety of PET/CT-guided percutaneous core bone biopsy and to compare the PET/CT-guided method to conventional CT-guided percutaneous core biopsies to diagnose Chinese patients with bone tumors and tumor-like lesion...
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| Format: | Article |
| Language: | English |
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BMC
2019-10-01
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| Series: | Cancer Imaging |
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| Online Access: | http://link.springer.com/article/10.1186/s40644-019-0253-1 |
| _version_ | 1818573662482071552 |
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| author | Min-hao Wu Ling-fei Xiao Huo-wen Liu Zhi-qiang Yang Xiao-xiao Liang Yan Chen Jun Lei Zhou-ming Deng |
| author_facet | Min-hao Wu Ling-fei Xiao Huo-wen Liu Zhi-qiang Yang Xiao-xiao Liang Yan Chen Jun Lei Zhou-ming Deng |
| author_sort | Min-hao Wu |
| collection | DOAJ |
| description | Abstract Objective The present study aimed to evaluate the diagnostic performance and safety of PET/CT-guided percutaneous core bone biopsy and to compare the PET/CT-guided method to conventional CT-guided percutaneous core biopsies to diagnose Chinese patients with bone tumors and tumor-like lesions. Methods Data for 97 patients with bone tumors and tumor-like lesions diagnosed by percutaneous core bone biopsy from February 2013 to November 2018 were retrospectively analyzed. The study included 42 cases in the PET/CT group and 55 cases in the CT alone group. The diagnostic performance, cost and complications associated with the intervention were compared between the two groups. All patients were eventually confirmed to have bone tumors and tumor-like lesions according to surgical pathology findings. Results There were no significant differences in patient characteristics (P > 0.05). For the patients in the PET/CT group, the overall diagnostic yield of the initial biopsies and the diagnostic accuracy derived from the surgically proven cases were both 97.62%, which was significantly higher than the values in the CT group during the same period (P < 0.05). No major biopsy-related complications (e.g., serious bleeding or tumor dissemination) occurred before, during, or after the intervention. Therefore, no significant difference was observed between the two groups with regard to the complication rate (P > 0.05). Conclusion Compared with CT-guided percutaneous bone biopsy, PET/CT-guided percutaneous bone biopsy is an effective and safe alternative with high diagnostic performance in the evaluation of hypermetabolic bone lesions to diagnose bone tumors and tumor-like lesions. |
| first_indexed | 2024-12-15T00:14:30Z |
| format | Article |
| id | doaj.art-8076f99b900049dc8542ef2341649b0b |
| institution | Directory Open Access Journal |
| issn | 1470-7330 |
| language | English |
| last_indexed | 2024-12-15T00:14:30Z |
| publishDate | 2019-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Cancer Imaging |
| spelling | doaj.art-8076f99b900049dc8542ef2341649b0b2022-12-21T22:42:28ZengBMCCancer Imaging1470-73302019-10-0119111210.1186/s40644-019-0253-1PET/CT-guided versus CT-guided percutaneous core biopsies in the diagnosis of bone tumors and tumor-like lesions: which is the better choice?Min-hao Wu0Ling-fei Xiao1Huo-wen Liu2Zhi-qiang Yang3Xiao-xiao Liang4Yan Chen5Jun Lei6Zhou-ming Deng7Department of Spine Surgery and Musculoskeletal Tumor, Zhongnan Hospital of Wuhan UniversityDepartment of Spine Surgery and Musculoskeletal Tumor, Zhongnan Hospital of Wuhan UniversityDepartment of Spine Surgery and Musculoskeletal Tumor, Zhongnan Hospital of Wuhan UniversityDepartment of Spine Surgery and Musculoskeletal Tumor, Zhongnan Hospital of Wuhan UniversityDepartment of Spine Surgery and Musculoskeletal Tumor, Zhongnan Hospital of Wuhan UniversityDepartment of Spine Surgery and Musculoskeletal Tumor, Zhongnan Hospital of Wuhan UniversityDepartment of Spine Surgery and Musculoskeletal Tumor, Zhongnan Hospital of Wuhan UniversityDepartment of Spine Surgery and Musculoskeletal Tumor, Zhongnan Hospital of Wuhan UniversityAbstract Objective The present study aimed to evaluate the diagnostic performance and safety of PET/CT-guided percutaneous core bone biopsy and to compare the PET/CT-guided method to conventional CT-guided percutaneous core biopsies to diagnose Chinese patients with bone tumors and tumor-like lesions. Methods Data for 97 patients with bone tumors and tumor-like lesions diagnosed by percutaneous core bone biopsy from February 2013 to November 2018 were retrospectively analyzed. The study included 42 cases in the PET/CT group and 55 cases in the CT alone group. The diagnostic performance, cost and complications associated with the intervention were compared between the two groups. All patients were eventually confirmed to have bone tumors and tumor-like lesions according to surgical pathology findings. Results There were no significant differences in patient characteristics (P > 0.05). For the patients in the PET/CT group, the overall diagnostic yield of the initial biopsies and the diagnostic accuracy derived from the surgically proven cases were both 97.62%, which was significantly higher than the values in the CT group during the same period (P < 0.05). No major biopsy-related complications (e.g., serious bleeding or tumor dissemination) occurred before, during, or after the intervention. Therefore, no significant difference was observed between the two groups with regard to the complication rate (P > 0.05). Conclusion Compared with CT-guided percutaneous bone biopsy, PET/CT-guided percutaneous bone biopsy is an effective and safe alternative with high diagnostic performance in the evaluation of hypermetabolic bone lesions to diagnose bone tumors and tumor-like lesions.http://link.springer.com/article/10.1186/s40644-019-0253-1Image-guided bone biopsyFDG PET/CTCT-guidedBone lesionsDiagnostic performanceComplications |
| spellingShingle | Min-hao Wu Ling-fei Xiao Huo-wen Liu Zhi-qiang Yang Xiao-xiao Liang Yan Chen Jun Lei Zhou-ming Deng PET/CT-guided versus CT-guided percutaneous core biopsies in the diagnosis of bone tumors and tumor-like lesions: which is the better choice? Cancer Imaging Image-guided bone biopsy FDG PET/CT CT-guided Bone lesions Diagnostic performance Complications |
| title | PET/CT-guided versus CT-guided percutaneous core biopsies in the diagnosis of bone tumors and tumor-like lesions: which is the better choice? |
| title_full | PET/CT-guided versus CT-guided percutaneous core biopsies in the diagnosis of bone tumors and tumor-like lesions: which is the better choice? |
| title_fullStr | PET/CT-guided versus CT-guided percutaneous core biopsies in the diagnosis of bone tumors and tumor-like lesions: which is the better choice? |
| title_full_unstemmed | PET/CT-guided versus CT-guided percutaneous core biopsies in the diagnosis of bone tumors and tumor-like lesions: which is the better choice? |
| title_short | PET/CT-guided versus CT-guided percutaneous core biopsies in the diagnosis of bone tumors and tumor-like lesions: which is the better choice? |
| title_sort | pet ct guided versus ct guided percutaneous core biopsies in the diagnosis of bone tumors and tumor like lesions which is the better choice |
| topic | Image-guided bone biopsy FDG PET/CT CT-guided Bone lesions Diagnostic performance Complications |
| url | http://link.springer.com/article/10.1186/s40644-019-0253-1 |
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