Arginyltransferase 1 modulates p62-driven autophagy via mTORC1/AMPk signaling

Arginyltransferase 1 modulates p62-driven autophagy via mTORC1/AMPk signaling

Abstract Background Arginyltransferase (Ate1) orchestrates posttranslational protein arginylation, a pivotal regulator of cellular proteolytic processes. In eukaryotic cells, two interconnected systems—the ubiquitin proteasome system (UPS) and macroautophagy—mediate proteolysis and cooperate to main...

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Bibliographic Details
Main Authors: Laura V. Bonnet, Anabela Palandri, Jesica B. Flores-Martin, Marta E. Hallak
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cell Communication and Signaling
Subjects:
Arginylation
Arginyltransferase 1
Autophagy
mTORC1
Posttranslational modification
p62/SQSTM1
Online Access:https://doi.org/10.1186/s12964-024-01499-9

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