<i>N</i>-Hydroxy-<i>N</i>-Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases

<i>N</i>-Hydroxy-<i>N</i>-Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases

Alzheimer’s disease (AD) is a complex disorder characterized by impaired neurotransmission in cholinergic and monoaminergic neurons, which, in combination with the accumulation of misfolded proteins and increased oxidative stress, leads to the typical features of the disease at the biomolecular leve...

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Bibliographic Details
Main Authors: Óscar M. Bautista-Aguilera, José M. Alonso, Marco Catto, Isabel Iriepa, Damijan Knez, Stanislav Gobec, José Marco-Contelles
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
cholinesterases
ferulic acid
molecular modelling
monoamine oxidase
radical-scavenger
antioxidant
Online Access:https://www.mdpi.com/1420-3049/27/21/7437

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