Peptide Targeting of PDZ-Dependent Interactions as Pharmacological Intervention in Immune-Related Diseases

Peptide Targeting of PDZ-Dependent Interactions as Pharmacological Intervention in Immune-Related Diseases

PDZ (postsynaptic density (PSD95), discs large (Dlg), and zonula occludens (ZO-1)-dependent interactions are widely distributed within different cell types and regulate a variety of cellular processes. To date, some of these interactions have been identified as targets of small molecules or peptides...

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Bibliographic Details
Main Authors: Luis H. Gutiérrez-González, Selma Rivas-Fuentes, Silvia Guzmán-Beltrán, Angélica Flores-Flores, Jorge Rosas-García, Teresa Santos-Mendoza
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Molecules
Subjects:
PDZ domains
PDZ-dependent interactions
peptide inhibitors
immune-related disorders
Online Access:https://www.mdpi.com/1420-3049/26/21/6367

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