Comparison of the Predictive Accuracy of Intraocular Lens Power Calculations after Phototherapeutic Keratectomy in Granular Corneal Dystrophy Type 2

Granular corneal dystrophy type 2 (GCD2) is an autosomal dominant disease affecting vision. Phototherapeutic keratectomy (PTK) is advantageous in removing vision-threatening corneal opacities and postponing keratoplasty; however, it potentially disturbs accurate intraocular lens (IOL) power calculat...

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Main Authors: Sook Hyun Yoon, Woo Kyung Jo, Tae-im Kim, Kyoung Yul Seo, Jinseok Choi, Ikhyun Jun, Eung Kweon Kim
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/12/2/584
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author Sook Hyun Yoon
Woo Kyung Jo
Tae-im Kim
Kyoung Yul Seo
Jinseok Choi
Ikhyun Jun
Eung Kweon Kim
author_facet Sook Hyun Yoon
Woo Kyung Jo
Tae-im Kim
Kyoung Yul Seo
Jinseok Choi
Ikhyun Jun
Eung Kweon Kim
author_sort Sook Hyun Yoon
collection DOAJ
description Granular corneal dystrophy type 2 (GCD2) is an autosomal dominant disease affecting vision. Phototherapeutic keratectomy (PTK) is advantageous in removing vision-threatening corneal opacities and postponing keratoplasty; however, it potentially disturbs accurate intraocular lens (IOL) power calculation in cataract surgery. The myopic/hyperopic Haigis-L method with or without the central island has been reported; nevertheless, an optimal method has not yet been established. To compare the predictive accuracy of post-PTK IOL power calculations in GCD2, the retrospective data of 30 eyes from July 2017 to December 2020 were analyzed. All GCD2-affected eyes underwent post-PTK standard cataract surgery using the WaveLight EX500 platform (Alcon Laboratories, Inc., Fort Worth, TX, USA) under a single surgeon. The mean prediction error (MPE) and absolute error (MAE) with the myopic/hyperopic Haigis-L, Barrett Universal II, Barrett True-K, Haigis, and SRK/T by standard keratometry (K) and total keratometry (TK), where possible, were analyzed. Barrett Universal II and SRK/T showed significantly superior MPE, and MAE compared with the myopic/hyperopic Haigis-L method. TK was not significantly superior to K in the same formula. In conclusion, this study suggests that these biometries and formulas, especially Barrett Universal II and SRK/T, are potentially useful in IOL power calculation in GCD2 after PTK.
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spelling doaj.art-807e3532405d4620904140eed25a86a02023-11-30T22:51:57ZengMDPI AGJournal of Clinical Medicine2077-03832023-01-0112258410.3390/jcm12020584Comparison of the Predictive Accuracy of Intraocular Lens Power Calculations after Phototherapeutic Keratectomy in Granular Corneal Dystrophy Type 2Sook Hyun Yoon0Woo Kyung Jo1Tae-im Kim2Kyoung Yul Seo3Jinseok Choi4Ikhyun Jun5Eung Kweon Kim6Department of Ophthalmology, School of Medicine, Daegu Catholic University, Daegu 42472, Republic of KoreaThe Institute of Vision Research, Department of Ophthalmology, College of Medicine, Yonsei University, Seoul 03722, Republic of KoreaThe Institute of Vision Research, Department of Ophthalmology, College of Medicine, Yonsei University, Seoul 03722, Republic of KoreaThe Institute of Vision Research, Department of Ophthalmology, College of Medicine, Yonsei University, Seoul 03722, Republic of KoreaSaevit Eye Hospital, Goyang-si 10447, Republic of KoreaThe Institute of Vision Research, Department of Ophthalmology, College of Medicine, Yonsei University, Seoul 03722, Republic of KoreaCorneal Dystrophy Research Institute, Yonsei University College of Medicine, Seoul 03722, Republic of KoreaGranular corneal dystrophy type 2 (GCD2) is an autosomal dominant disease affecting vision. Phototherapeutic keratectomy (PTK) is advantageous in removing vision-threatening corneal opacities and postponing keratoplasty; however, it potentially disturbs accurate intraocular lens (IOL) power calculation in cataract surgery. The myopic/hyperopic Haigis-L method with or without the central island has been reported; nevertheless, an optimal method has not yet been established. To compare the predictive accuracy of post-PTK IOL power calculations in GCD2, the retrospective data of 30 eyes from July 2017 to December 2020 were analyzed. All GCD2-affected eyes underwent post-PTK standard cataract surgery using the WaveLight EX500 platform (Alcon Laboratories, Inc., Fort Worth, TX, USA) under a single surgeon. The mean prediction error (MPE) and absolute error (MAE) with the myopic/hyperopic Haigis-L, Barrett Universal II, Barrett True-K, Haigis, and SRK/T by standard keratometry (K) and total keratometry (TK), where possible, were analyzed. Barrett Universal II and SRK/T showed significantly superior MPE, and MAE compared with the myopic/hyperopic Haigis-L method. TK was not significantly superior to K in the same formula. In conclusion, this study suggests that these biometries and formulas, especially Barrett Universal II and SRK/T, are potentially useful in IOL power calculation in GCD2 after PTK.https://www.mdpi.com/2077-0383/12/2/584granular corneal dystrophyphototherapeutic keratectomyIOL power calculation
spellingShingle Sook Hyun Yoon
Woo Kyung Jo
Tae-im Kim
Kyoung Yul Seo
Jinseok Choi
Ikhyun Jun
Eung Kweon Kim
Comparison of the Predictive Accuracy of Intraocular Lens Power Calculations after Phototherapeutic Keratectomy in Granular Corneal Dystrophy Type 2
Journal of Clinical Medicine
granular corneal dystrophy
phototherapeutic keratectomy
IOL power calculation
title Comparison of the Predictive Accuracy of Intraocular Lens Power Calculations after Phototherapeutic Keratectomy in Granular Corneal Dystrophy Type 2
title_full Comparison of the Predictive Accuracy of Intraocular Lens Power Calculations after Phototherapeutic Keratectomy in Granular Corneal Dystrophy Type 2
title_fullStr Comparison of the Predictive Accuracy of Intraocular Lens Power Calculations after Phototherapeutic Keratectomy in Granular Corneal Dystrophy Type 2
title_full_unstemmed Comparison of the Predictive Accuracy of Intraocular Lens Power Calculations after Phototherapeutic Keratectomy in Granular Corneal Dystrophy Type 2
title_short Comparison of the Predictive Accuracy of Intraocular Lens Power Calculations after Phototherapeutic Keratectomy in Granular Corneal Dystrophy Type 2
title_sort comparison of the predictive accuracy of intraocular lens power calculations after phototherapeutic keratectomy in granular corneal dystrophy type 2
topic granular corneal dystrophy
phototherapeutic keratectomy
IOL power calculation
url https://www.mdpi.com/2077-0383/12/2/584
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