Surface Characterization, Biocompatibility and Antifungal Efficacy of a Denture-Lining Material Containing <i>Cnidium officinale</i> Extracts
Herein, we investigated the surface characterization and biocompatibility of a denture-lining material containing <i>Cnidium officinale</i> extracts and its antifungal efficacy against <i>Candida albicans</i>. To achieve this, a denture-lining material containing various conc...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-03-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/26/5/1440 |
| _version_ | 1797412847164063744 |
|---|---|
| author | Myung-Jin Lee Youn-Soo Shim So-Youn An Min-Kyung Kang |
| author_facet | Myung-Jin Lee Youn-Soo Shim So-Youn An Min-Kyung Kang |
| author_sort | Myung-Jin Lee |
| collection | DOAJ |
| description | Herein, we investigated the surface characterization and biocompatibility of a denture-lining material containing <i>Cnidium officinale</i> extracts and its antifungal efficacy against <i>Candida albicans</i>. To achieve this, a denture-lining material containing various concentrations of <i>C. officinale</i> extract and a control group without <i>C. officinale</i> extract were prepared. The surface characterization and biocompatibility of the samples were investigated. In addition, the antifungal efficacy of the samples on <i>C. albicans</i> was investigated using spectrophotometric growth and a LIVE/DEAD assay. The results revealed that there was no significant difference between the biocompatibility of the experimental and control groups (<i>p</i> > 0.05). However, there was a significant difference between the antifungal efficiency of the denture material on <i>C. albicans</i> and that of the control group (<i>p</i> < 0.05), which was confirmed by the LIVE/DEAD assay. These results indicate the promising potential of the <i>C. officinale</i> extract-containing denture-lining material as an antifungal dental material. |
| first_indexed | 2024-03-09T05:09:09Z |
| format | Article |
| id | doaj.art-80837659e3db44b5b6db08027f01fa1c |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T05:09:09Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-80837659e3db44b5b6db08027f01fa1c2023-12-03T12:51:59ZengMDPI AGMolecules1420-30492021-03-01265144010.3390/molecules26051440Surface Characterization, Biocompatibility and Antifungal Efficacy of a Denture-Lining Material Containing <i>Cnidium officinale</i> ExtractsMyung-Jin Lee0Youn-Soo Shim1So-Youn An2Min-Kyung Kang3Department of Dental Hygiene, Division of Health Science, Baekseok University, Cheonan 31065, Chungcheongnam-do, KoreaDepartment of Dental Hygiene, Sunmoon University, Asan 31460, Chungcheongnam-do, KoreaDepartment of Pediatric Dentristry, College of Dentistry, Wonkwang University, Iksan-si 5453, Jeollabuk-do, KoreaDepartment of Dental Hygiene, Hanseo University, Seosan 31963, Chungcheongnam-do, KoreaHerein, we investigated the surface characterization and biocompatibility of a denture-lining material containing <i>Cnidium officinale</i> extracts and its antifungal efficacy against <i>Candida albicans</i>. To achieve this, a denture-lining material containing various concentrations of <i>C. officinale</i> extract and a control group without <i>C. officinale</i> extract were prepared. The surface characterization and biocompatibility of the samples were investigated. In addition, the antifungal efficacy of the samples on <i>C. albicans</i> was investigated using spectrophotometric growth and a LIVE/DEAD assay. The results revealed that there was no significant difference between the biocompatibility of the experimental and control groups (<i>p</i> > 0.05). However, there was a significant difference between the antifungal efficiency of the denture material on <i>C. albicans</i> and that of the control group (<i>p</i> < 0.05), which was confirmed by the LIVE/DEAD assay. These results indicate the promising potential of the <i>C. officinale</i> extract-containing denture-lining material as an antifungal dental material.https://www.mdpi.com/1420-3049/26/5/1440antifungal efficacybiocompatibility<i>Candida albicans</i><i>Cnidium officinale</i>denture-relining materialsurface characterization |
| spellingShingle | Myung-Jin Lee Youn-Soo Shim So-Youn An Min-Kyung Kang Surface Characterization, Biocompatibility and Antifungal Efficacy of a Denture-Lining Material Containing <i>Cnidium officinale</i> Extracts Molecules antifungal efficacy biocompatibility <i>Candida albicans</i> <i>Cnidium officinale</i> denture-relining material surface characterization |
| title | Surface Characterization, Biocompatibility and Antifungal Efficacy of a Denture-Lining Material Containing <i>Cnidium officinale</i> Extracts |
| title_full | Surface Characterization, Biocompatibility and Antifungal Efficacy of a Denture-Lining Material Containing <i>Cnidium officinale</i> Extracts |
| title_fullStr | Surface Characterization, Biocompatibility and Antifungal Efficacy of a Denture-Lining Material Containing <i>Cnidium officinale</i> Extracts |
| title_full_unstemmed | Surface Characterization, Biocompatibility and Antifungal Efficacy of a Denture-Lining Material Containing <i>Cnidium officinale</i> Extracts |
| title_short | Surface Characterization, Biocompatibility and Antifungal Efficacy of a Denture-Lining Material Containing <i>Cnidium officinale</i> Extracts |
| title_sort | surface characterization biocompatibility and antifungal efficacy of a denture lining material containing i cnidium officinale i extracts |
| topic | antifungal efficacy biocompatibility <i>Candida albicans</i> <i>Cnidium officinale</i> denture-relining material surface characterization |
| url | https://www.mdpi.com/1420-3049/26/5/1440 |
| work_keys_str_mv | AT myungjinlee surfacecharacterizationbiocompatibilityandantifungalefficacyofadentureliningmaterialcontainingicnidiumofficinaleiextracts AT younsooshim surfacecharacterizationbiocompatibilityandantifungalefficacyofadentureliningmaterialcontainingicnidiumofficinaleiextracts AT soyounan surfacecharacterizationbiocompatibilityandantifungalefficacyofadentureliningmaterialcontainingicnidiumofficinaleiextracts AT minkyungkang surfacecharacterizationbiocompatibilityandantifungalefficacyofadentureliningmaterialcontainingicnidiumofficinaleiextracts |