A multi-omics analysis of recombinant protein production in Hek293 cells.

Hek293 cells are the predominant hosts for transient expression of recombinant proteins and are used for stable expression of proteins where post-translational modifications performed by CHO cells are inadequate. Nevertheless, there is little information available on the key cellular features underp...

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Bibliographic Details
Main Authors: Stefanie Dietmair, Mark P Hodson, Lake-Ee Quek, Nicholas E Timmins, Peter Gray, Lars K Nielsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3427347?pdf=render