Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review
Metastases are the main type of malignancy involving bone, which is the third most frequent site of metastatic carcinoma, after lung and liver. Skeletal-related events such as intractable pain, spinal cord compression, and pathologic fractures pose a serious burden on patients’ quality of life. For...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Current Oncology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1718-7729/29/6/332 |
| _version_ | 1797488450318893056 |
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| author | Nicolas Papalexis Anna Parmeggiani Giuliano Peta Paolo Spinnato Marco Miceli Giancarlo Facchini |
| author_facet | Nicolas Papalexis Anna Parmeggiani Giuliano Peta Paolo Spinnato Marco Miceli Giancarlo Facchini |
| author_sort | Nicolas Papalexis |
| collection | DOAJ |
| description | Metastases are the main type of malignancy involving bone, which is the third most frequent site of metastatic carcinoma, after lung and liver. Skeletal-related events such as intractable pain, spinal cord compression, and pathologic fractures pose a serious burden on patients’ quality of life. For this reason, mini-invasive treatments for the management of bone metastases were developed with the goal of pain relief and functional status improvement. These techniques include embolization, thermal ablation, electrochemotherapy, cementoplasty, and MRI-guided high-intensity focused ultrasound. In order to achieve durable pain palliation and disease control, mini-invasive procedures are combined with chemotherapy, radiation therapy, surgery, or analgesics. The purpose of this review is to summarize the recently published literature regarding interventional radiology procedures in the treatment of cancer patients with bone metastases, focusing on the efficacy, complications, local disease control and recurrence rate. |
| first_indexed | 2024-03-10T00:02:25Z |
| format | Article |
| id | doaj.art-8092178312074a7e9fcd0f26b5226943 |
| institution | Directory Open Access Journal |
| issn | 1198-0052 1718-7729 |
| language | English |
| last_indexed | 2024-03-10T00:02:25Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj.art-8092178312074a7e9fcd0f26b52269432023-11-23T16:14:06ZengMDPI AGCurrent Oncology1198-00521718-77292022-06-012964155417710.3390/curroncol29060332Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive ReviewNicolas Papalexis0Anna Parmeggiani1Giuliano Peta2Paolo Spinnato3Marco Miceli4Giancarlo Facchini5Diagnostic and Interventional Radiology Unit, IRCCS Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, ItalyDiagnostic and Interventional Radiology Unit, IRCCS Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, ItalyDiagnostic and Interventional Radiology Unit, IRCCS Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, ItalyDiagnostic and Interventional Radiology Unit, IRCCS Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, ItalyDiagnostic and Interventional Radiology Unit, IRCCS Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, ItalyDiagnostic and Interventional Radiology Unit, IRCCS Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, ItalyMetastases are the main type of malignancy involving bone, which is the third most frequent site of metastatic carcinoma, after lung and liver. Skeletal-related events such as intractable pain, spinal cord compression, and pathologic fractures pose a serious burden on patients’ quality of life. For this reason, mini-invasive treatments for the management of bone metastases were developed with the goal of pain relief and functional status improvement. These techniques include embolization, thermal ablation, electrochemotherapy, cementoplasty, and MRI-guided high-intensity focused ultrasound. In order to achieve durable pain palliation and disease control, mini-invasive procedures are combined with chemotherapy, radiation therapy, surgery, or analgesics. The purpose of this review is to summarize the recently published literature regarding interventional radiology procedures in the treatment of cancer patients with bone metastases, focusing on the efficacy, complications, local disease control and recurrence rate.https://www.mdpi.com/1718-7729/29/6/332bone metastasesimaginginterventional radiologyablation techniquesembolizationhigh-intensity focused ultrasound ablation |
| spellingShingle | Nicolas Papalexis Anna Parmeggiani Giuliano Peta Paolo Spinnato Marco Miceli Giancarlo Facchini Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review Current Oncology bone metastases imaging interventional radiology ablation techniques embolization high-intensity focused ultrasound ablation |
| title | Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review |
| title_full | Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review |
| title_fullStr | Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review |
| title_full_unstemmed | Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review |
| title_short | Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review |
| title_sort | minimally invasive interventional procedures for metastatic bone disease a comprehensive review |
| topic | bone metastases imaging interventional radiology ablation techniques embolization high-intensity focused ultrasound ablation |
| url | https://www.mdpi.com/1718-7729/29/6/332 |
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