Neonatal thrombocytopenia and platelets transfusion
Background: Neonates often develop thrombocytopenia at some time during hospital stay. Platelet transfusion are frequently given to them and are likely to result in unnecessary transfusion. Material and Methods: Thus, we analyzed thrombocytopenia in neonates, its prevalence, and relationship if any,...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-01-01
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| Series: | Asian Journal of Transfusion Science |
| Subjects: | |
| Online Access: | http://www.ajts.org/article.asp?issn=0973-6247;year=2012;volume=6;issue=2;spage=161;epage=164;aulast=Gupta |
| _version_ | 1811266772795392000 |
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| author | Anil K Gupta Sudarshan Kumari Abhishek Singhal Aruna Bahl |
| author_facet | Anil K Gupta Sudarshan Kumari Abhishek Singhal Aruna Bahl |
| author_sort | Anil K Gupta |
| collection | DOAJ |
| description | Background: Neonates often develop thrombocytopenia at some time during hospital stay. Platelet transfusion are frequently given to them and are likely to result in unnecessary transfusion. Material and Methods: Thus, we analyzed thrombocytopenia in neonates, its prevalence, and relationship if any, between clinical condition and platelet transfusion in neonates, which would have been helpful in developing guidelines and/or protocols for platelet transfusion (and reducing the donor exposure) in neonates. Results: A total of 870 neonates who were admitted in Neonatal Intensive Care Unit (NICU) with various morbidities had platelets count done; of these, 146 (16.7%) neonate revealed thrombocytopenia. Discussion: Low birth weight babies (P 0.009) and babies born with mother having hypertension (P 0.04) showed significant thrombocytopenia. Neonates with intrauterine growth retardation (IUGR) diagnosed during antenatal screening showed lower platelet count (P 0.022). Neonates having associated illness, such as sepsis, gastrointestinal, and respiratory problems, and on vasopressor drugs were found to be associated with low platelet count. Conclusion: In our study, 16.40% of thrombocytopenic neonates required platelet transfusion either alone or with other blood component during their stay in NICU. |
| first_indexed | 2024-04-12T20:49:21Z |
| format | Article |
| id | doaj.art-8093ff579c0f4d8098e85c4383039636 |
| institution | Directory Open Access Journal |
| issn | 0973-6247 1998-3565 |
| language | English |
| last_indexed | 2024-04-12T20:49:21Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Journal of Transfusion Science |
| spelling | doaj.art-8093ff579c0f4d8098e85c43830396362022-12-22T03:17:11ZengWolters Kluwer Medknow PublicationsAsian Journal of Transfusion Science0973-62471998-35652012-01-016216116410.4103/0973-6247.98924Neonatal thrombocytopenia and platelets transfusionAnil K GuptaSudarshan KumariAbhishek SinghalAruna BahlBackground: Neonates often develop thrombocytopenia at some time during hospital stay. Platelet transfusion are frequently given to them and are likely to result in unnecessary transfusion. Material and Methods: Thus, we analyzed thrombocytopenia in neonates, its prevalence, and relationship if any, between clinical condition and platelet transfusion in neonates, which would have been helpful in developing guidelines and/or protocols for platelet transfusion (and reducing the donor exposure) in neonates. Results: A total of 870 neonates who were admitted in Neonatal Intensive Care Unit (NICU) with various morbidities had platelets count done; of these, 146 (16.7%) neonate revealed thrombocytopenia. Discussion: Low birth weight babies (P 0.009) and babies born with mother having hypertension (P 0.04) showed significant thrombocytopenia. Neonates with intrauterine growth retardation (IUGR) diagnosed during antenatal screening showed lower platelet count (P 0.022). Neonates having associated illness, such as sepsis, gastrointestinal, and respiratory problems, and on vasopressor drugs were found to be associated with low platelet count. Conclusion: In our study, 16.40% of thrombocytopenic neonates required platelet transfusion either alone or with other blood component during their stay in NICU.http://www.ajts.org/article.asp?issn=0973-6247;year=2012;volume=6;issue=2;spage=161;epage=164;aulast=GuptaNeonatal transfusionplatelet transfusionthrombocytopenia |
| spellingShingle | Anil K Gupta Sudarshan Kumari Abhishek Singhal Aruna Bahl Neonatal thrombocytopenia and platelets transfusion Asian Journal of Transfusion Science Neonatal transfusion platelet transfusion thrombocytopenia |
| title | Neonatal thrombocytopenia and platelets transfusion |
| title_full | Neonatal thrombocytopenia and platelets transfusion |
| title_fullStr | Neonatal thrombocytopenia and platelets transfusion |
| title_full_unstemmed | Neonatal thrombocytopenia and platelets transfusion |
| title_short | Neonatal thrombocytopenia and platelets transfusion |
| title_sort | neonatal thrombocytopenia and platelets transfusion |
| topic | Neonatal transfusion platelet transfusion thrombocytopenia |
| url | http://www.ajts.org/article.asp?issn=0973-6247;year=2012;volume=6;issue=2;spage=161;epage=164;aulast=Gupta |
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