High-dose-rate interstitial brachytherapy as a suitable option for metastatic extraskeletal myxoid chondrosarcoma – a case report

We report on a patient with metastatic extraskeletal myxoid chondrosarcoma (EMC), who was treated with palliative high-dose-rate (HDR) interstitial brachytherapy (ISBT). The patient was an 87-year-old woman who underwent an amputation for a bulky tumor in her right ankle joint. EMC was histopatholog...

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Main Authors: Yoshiaki Takagawa, Naoya Murakami, Hiroshi Igaki, Hiroyuki Okamoto, Jun Itami
Format: Article
Language:English
Published: Termedia Publishing House 2022-03-01
Series:Journal of Contemporary Brachytherapy
Subjects:
Online Access:https://www.termedia.pl/High-dose-rate-interstitial-brachytherapy-as-a-suitable-option-for-metastatic-extraskeletal-myxoid-chondrosarcoma-a-case-report,54,46791,1,1.html
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author Yoshiaki Takagawa
Naoya Murakami
Hiroshi Igaki
Hiroyuki Okamoto
Jun Itami
author_facet Yoshiaki Takagawa
Naoya Murakami
Hiroshi Igaki
Hiroyuki Okamoto
Jun Itami
author_sort Yoshiaki Takagawa
collection DOAJ
description We report on a patient with metastatic extraskeletal myxoid chondrosarcoma (EMC), who was treated with palliative high-dose-rate (HDR) interstitial brachytherapy (ISBT). The patient was an 87-year-old woman who underwent an amputation for a bulky tumor in her right ankle joint. EMC was histopathologically confirmed. She presented with a large right inguinal lymph node metastasis of EMC 16 months after surgery. Palliative HDR-ISBT (30 Gy/2 fractions in 1 day) for the right inguinal lymph node metastasis was administered to shorten treatment period. Additional HDR-ISBT (30 Gy/2 fractions in 1 day) was administered for the management of subsequent subcutaneous metastasis to the right breast and right popliteal fossa. HDR-ISBT provided significant long-term control of the recurrent tumor in all three sites, without severe acute and late toxicity. Thus, HDR-ISBT regimen of 30 Gy/2 fractions in 1 day can be a suitable option for both palliation and long-term local control for patients with metastatic EMC.
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spelling doaj.art-80974d3d104c4ac79a175e8513a0bdca2022-12-22T02:23:28ZengTermedia Publishing HouseJournal of Contemporary Brachytherapy1689-832X2081-28412022-03-0114219820410.5114/jcb.2022.11516146791High-dose-rate interstitial brachytherapy as a suitable option for metastatic extraskeletal myxoid chondrosarcoma – a case reportYoshiaki TakagawaNaoya MurakamiHiroshi IgakiHiroyuki OkamotoJun ItamiWe report on a patient with metastatic extraskeletal myxoid chondrosarcoma (EMC), who was treated with palliative high-dose-rate (HDR) interstitial brachytherapy (ISBT). The patient was an 87-year-old woman who underwent an amputation for a bulky tumor in her right ankle joint. EMC was histopathologically confirmed. She presented with a large right inguinal lymph node metastasis of EMC 16 months after surgery. Palliative HDR-ISBT (30 Gy/2 fractions in 1 day) for the right inguinal lymph node metastasis was administered to shorten treatment period. Additional HDR-ISBT (30 Gy/2 fractions in 1 day) was administered for the management of subsequent subcutaneous metastasis to the right breast and right popliteal fossa. HDR-ISBT provided significant long-term control of the recurrent tumor in all three sites, without severe acute and late toxicity. Thus, HDR-ISBT regimen of 30 Gy/2 fractions in 1 day can be a suitable option for both palliation and long-term local control for patients with metastatic EMC.https://www.termedia.pl/High-dose-rate-interstitial-brachytherapy-as-a-suitable-option-for-metastatic-extraskeletal-myxoid-chondrosarcoma-a-case-report,54,46791,1,1.htmlextraskeletal myxoid chondrosarcoma palliation high-dose-rate interstitial brachytherapy
spellingShingle Yoshiaki Takagawa
Naoya Murakami
Hiroshi Igaki
Hiroyuki Okamoto
Jun Itami
High-dose-rate interstitial brachytherapy as a suitable option for metastatic extraskeletal myxoid chondrosarcoma – a case report
Journal of Contemporary Brachytherapy
extraskeletal myxoid chondrosarcoma
palliation
high-dose-rate
interstitial brachytherapy
title High-dose-rate interstitial brachytherapy as a suitable option for metastatic extraskeletal myxoid chondrosarcoma – a case report
title_full High-dose-rate interstitial brachytherapy as a suitable option for metastatic extraskeletal myxoid chondrosarcoma – a case report
title_fullStr High-dose-rate interstitial brachytherapy as a suitable option for metastatic extraskeletal myxoid chondrosarcoma – a case report
title_full_unstemmed High-dose-rate interstitial brachytherapy as a suitable option for metastatic extraskeletal myxoid chondrosarcoma – a case report
title_short High-dose-rate interstitial brachytherapy as a suitable option for metastatic extraskeletal myxoid chondrosarcoma – a case report
title_sort high dose rate interstitial brachytherapy as a suitable option for metastatic extraskeletal myxoid chondrosarcoma a case report
topic extraskeletal myxoid chondrosarcoma
palliation
high-dose-rate
interstitial brachytherapy
url https://www.termedia.pl/High-dose-rate-interstitial-brachytherapy-as-a-suitable-option-for-metastatic-extraskeletal-myxoid-chondrosarcoma-a-case-report,54,46791,1,1.html
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