Therapeutic inertia in type 2 diabetes: prevalence, causes, consequences and methods to overcome inertia

Early glycaemic control leads to better outcomes, including a reduction in long-term macrovascular and microvascular complications. Despite good-quality evidence, glycaemic control has been shown to be inadequate globally. Therapeutic inertia has been shown present in all stages of treatment intensi...

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Main Authors: Sachin Khunti, Kamlesh Khunti, Samuel Seidu
Format: Article
Language:English
Published: SAGE Publishing 2019-05-01
Series:Therapeutic Advances in Endocrinology and Metabolism
Online Access:https://doi.org/10.1177/2042018819844694
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author Sachin Khunti
Kamlesh Khunti
Samuel Seidu
author_facet Sachin Khunti
Kamlesh Khunti
Samuel Seidu
author_sort Sachin Khunti
collection DOAJ
description Early glycaemic control leads to better outcomes, including a reduction in long-term macrovascular and microvascular complications. Despite good-quality evidence, glycaemic control has been shown to be inadequate globally. Therapeutic inertia has been shown present in all stages of treatment intensification, from the first oral antihyperglycaemic drug (OAD), all the way to the initiation of insulin. The causes and possible solutions to the problem of therapeutic inertia are complex but can be understood better when viewed from the perspective of the providers [healthcare professionals (HCPs)], patients and healthcare systems. In this review, we will discuss the possible aetiologies, consequences and solutions of therapeutic inertia, drawing upon evidence from published literature on the subject of type 2 diabetes.
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spelling doaj.art-809ae836afd74a65b96829e319ad9a152022-12-21T17:50:31ZengSAGE PublishingTherapeutic Advances in Endocrinology and Metabolism2042-01962019-05-011010.1177/2042018819844694Therapeutic inertia in type 2 diabetes: prevalence, causes, consequences and methods to overcome inertiaSachin KhuntiKamlesh KhuntiSamuel SeiduEarly glycaemic control leads to better outcomes, including a reduction in long-term macrovascular and microvascular complications. Despite good-quality evidence, glycaemic control has been shown to be inadequate globally. Therapeutic inertia has been shown present in all stages of treatment intensification, from the first oral antihyperglycaemic drug (OAD), all the way to the initiation of insulin. The causes and possible solutions to the problem of therapeutic inertia are complex but can be understood better when viewed from the perspective of the providers [healthcare professionals (HCPs)], patients and healthcare systems. In this review, we will discuss the possible aetiologies, consequences and solutions of therapeutic inertia, drawing upon evidence from published literature on the subject of type 2 diabetes.https://doi.org/10.1177/2042018819844694
spellingShingle Sachin Khunti
Kamlesh Khunti
Samuel Seidu
Therapeutic inertia in type 2 diabetes: prevalence, causes, consequences and methods to overcome inertia
Therapeutic Advances in Endocrinology and Metabolism
title Therapeutic inertia in type 2 diabetes: prevalence, causes, consequences and methods to overcome inertia
title_full Therapeutic inertia in type 2 diabetes: prevalence, causes, consequences and methods to overcome inertia
title_fullStr Therapeutic inertia in type 2 diabetes: prevalence, causes, consequences and methods to overcome inertia
title_full_unstemmed Therapeutic inertia in type 2 diabetes: prevalence, causes, consequences and methods to overcome inertia
title_short Therapeutic inertia in type 2 diabetes: prevalence, causes, consequences and methods to overcome inertia
title_sort therapeutic inertia in type 2 diabetes prevalence causes consequences and methods to overcome inertia
url https://doi.org/10.1177/2042018819844694
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AT samuelseidu therapeuticinertiaintype2diabetesprevalencecausesconsequencesandmethodstoovercomeinertia